In a guest Alien Loves Predator strip, a mugger pulls a gun on Abe and Preston while they are talking about crime in New York. The mugger quickly asks if the gun is theirs, while Preston's Plasmacaster accidentally targets his head.
Mocked in Another Gaming Comic. Within the tabletop game the characters play, poorly-equipped bandits attack a group of "flying, flaming weaponmasters" — a standard D&D party. "They're bandits, not brain surgeons."
Gunnerkrigg Court once had senior schoolkids mocking Annie and Kat. And the "teddy", which was a doll possessed by the spirit bored out of his mind for years and now also annoyed. And somewhat shapeshifting. Quoth the big guy on the next page, "I absolutely did not expect thiiiiis!" (comment below: "I bet that guy wasn't expecting that.")
Xykon: ...and it turned out oops! He was also an archmage! Needless to say, hilarity ensued.
In Tales of the Questor, a group of angry townspeople catch Quentyn trying to flee with their prisoner. Quentyn warns them off with his elfshot pistol. The lead roughneck laughs in his face — only to be pincushioned a moment later.
Schlock Mercenary: This happens a lot, seeing as how the protagonists are heavily armed mercenaries.
Such an happenstance incidentally turns something the mercs are not good at (a formal dinner) into something that they are very, very good at. Note this continues to happen occasionally, only these days the mercs tend to be wearing power armor (it looks just like the uniforms they wore before that weren't armor... so it stays this trope).
While acquiring Schlock some new eyes (after his were gouged out in a particularly brutal fight) the Toughs are continually faced with a more numerous but far less able enemy. Culminates in the enemy fleet attacking Petey in the mistaken belief that any ex-Tausennigan warship can't possibly have a working AI. A visual metaphor is provided.
Emily Watson's Establishing Character Moment in Spacetrawler. Two guys with knives tell her to hand over her wallet; she whips out a pair of handguns and demands her would-be muggers' wallets and car keys.
Occurs off-camera in Times Like This, when a burglar breaks into the apartment of a master swords-woman, who is home, surrounded by some of her favourite weapons. The news reports then describe the would be robber as a one-armed bandit.
A foxwoman finds a young man going to visit his grandmother. She takes human form, lures him with the promise of random sex, and then shifts into her foxwoman form, making it look she's going to eat him. Turns out the man is a shapeshifted dragon.
A London street gang pull this on Susan/Anna Enfield during the second chapter of Sire. Susan rightfully boasts that she has already killed two people with her bare hands and is not afraid to make it three.
Because eating others is perfectly legal in the Crapsaccharine World of Kevin & Kell, this is a fairly common event, making one wonder why anyone in general would be a crook, since it's perfectly legal for the police or your victims to eat you if they can. Two notable events we see are one of the earliest comics, where Kell deliberately leaves her home unlocked to lure in stupid thieves to sate her pregnancy cravings, and one after Danielle joins the cast, where a puma that tries to eat her ends up being made into mincemeat and eaten by her instead.