Seeing the Decepticons get drunk on Energon in "Micro-Bots" is probably one of the funniest moments in Transformers history. Megatron slurs his words and rambles about Cybertron being "The Home of the Metal Moon" and Laserbeak flies like he's drunk and crashes.
Megatron (to Starscream): "You're either lying, or you're stupid!"
In "Enter the Nightbird", there's a scene where all of the first season Autobots chase Nightbird up a cliff. The one Autobot that needs help getting up the cliff? Cliffjumper.
In "Megatron's Master Plan", there's a scene with Soundwave and all his tapes at a dance club. Rumble's dancing, Soundwave's chillin' with the ladies and some random guy asks Laserbeak if he wants a cracker. Laserbeak's eyes glow in response. This reaction could be interpreted as anything from "I will destroy you, human" to "Mmm, crackers..."