VICTOR VON DOOM. Almost everything he does is hilarious, mostly because he is nothing like the actual Victor von Doom. To the point where one has to ask: "Is this a malfunctioning Doombot that wandered out of Latveria and wound up in southern California?"
Doctor Doom Assist Me:
A lamenting Doom shows Max a childish drawing he made of him and Strider which prompts Max to show his even better drawing. Doom is not pleased.
How about this interaction when Max checks out Doom in the bathroom, thus leaving this response :
Max implying that X-23 pays for things with her...y'know. X-23 promptly pulls out her claws.
Doom falling for X-23 and Max watching him. To clarify, Doom sees X-23 eating some yogurt and making sexy faces in Doom's direction. Max, on the other hand, sees her just eating the yogurt like an animal and not attractively in any way.
Max: She's all yours, buddy.
And then reversed when X-23 learns that Doom defeated Wesker. She sees him drinking from a chalice, Max sees him drinking milk straight from the carton and belching.
Rocket Raccoon in general. A cute little puppet being characterized as one of the most foul-mouthed and aggressive characters in the entire series is just hilarious. Even more when he outright mauls Doom's face in the middle of Max's battle against Galactus.
Deadpool answers the door and finds a bunch of nerds petitioning for Capcom to add more characters. Deadpool at first seems set to sign but when the nerds start getting excited about getting Mega Man, Deadpool shoots them and we get this exchange.
Max: Oh God, it must be those Mega Man kids again!
The Mega Man kids from the Deadpool episode show up again as zombies and still keep their obession about getting him added in. Doom tells them to get over it and shoots them with the finger lasers.
Phoenix Assist Me:
Max trying to remember who "Jean" was, then having it hit him and hearing Yipes yell her name in his head. As soon Max realizes Jean is Phoenix he screams in horror and jump the hell away from her.
Doom: Heh. *shrugs. That's never happened before.
After telling Doom who Jean is, this happens :
Doom: We need a roommate, you look mighty high. So Doom was going to take you upstairs to show his finger lasers but my roommate informs me that you're a fire-breathing, galaxy-destroying, level 5 Bitch from Hell. (Background music cuts out.) So we're gonna need you to take a hike. We cool?
Max: (Nodded to himself) We're dead!
The scene with the movie montage. Showing Phoenix's horrible performance in X-Men: The Last Stand? Bad. Showing Doom's even suckier performance in the 2005Fantastic Fourmovie? Worse. But then we get "Max's" performances in a bunch of horrible scenes in several Nicolas Cage movies. Doom puts it best:
Wesker pulls out a receipt from his longcoat and learns that he, while drunk, purchased the tattoo himself for $600, leading to a good laugh from X-23. But then Wesker asks her and Doom to check their receipts and X-23 pulls one out from her Victoria's Secret Compartment (since she doesn't have pockets) to find out, to her embarrassment, that she drew out $800 from a Bellagio A.T.M.: $200 more than the price for Wesker's ink, earning her an Evil Laugh from the mad scientist.
During the Q&A, one person asked Phoenix if she could marry him.
Rocket Raccoon apparently passed out after being really drunk, followed by a slurred "It's Vegas baby!"
Thanos doesn't take defeat well, and in the scuffle between him and Max (who beat him withan infinite), Doom gets hit by the door to Family Fun Arcade (which has since closed, alas). Twice.
Max has a Sadistic Choicenot really. What's more important thousands of lives or videogames? Considering the page this is under the answer should be obvious.
Doom literally grinds some of Max's games for homemade Infinity Gems (as the Time Gem already on Doom's person has stopped working altogether), with the Super Nintendo games actually producing results: Street Fighter II gives him plutonium (no good as the Infinity Gauntlet runs on comic book logic) which Doom carelessly throws behind him. Street Fighter Alpha 2 gives him one gem (the wrong kind). Then Max stumbles upon Marvel Super Heroes War Of The Gems — the perfect game for the job, as it yields a number of gems.
(Both Maxes scream at each other until Redneck!Max passes out.)
Spanish Doom. Just Spanish Doom...and not to forget Max's blank-faced reaction to it. Equally funny when that disguise was able to help Hiryu escape Wesker when he was about to be apprehended. And when Doom fails to convince Wesker to be a biologist, this is what Doom says :
In the review for Injustice, Batman (Kevin Conroy's version) has taken Max and Doom hostage and orders them to talk. While Batman is interrogating Doom, Doom vows that it will be hard for Batman to mentally break Doom. Batman then decides to bring Key Lime flavored yogurt, and slowly spills it all in front of Doom, Doom begging Batman to stop. Doom relents, but Batman has another plan as he holds a My Little Pony doll of Rarity. Doom fearfully asks what Bats is going to do it. He cuts Rarity's hair with his Batarang, making Doom break down into tears. You can view it here.
Batman: What the hell is wrong with you anyway? You're a grown-ass man watching a cartoon show for little girls.