Beastmen Hunters. Being aware that there is Fantastic Racism in this world is one thing. To see that it goes so far that no one has an issue with Beastmen being murdered in public is another.
Your best friend turns into something inhuman and is shoved into a van right before your eyes. Then soon after, you look down to see your hands have turned into paws...
Beastchildren trafficking is very alive and well in Anima City. Michiru and Shirou may have prevented one shipment from happening, but there are probably dozens of beastchildren out there who weren't so lucky.
The Silver Wolf Order being a popular and gigantic cult that promises a better lifestyle for beastmen living in poverty and fear. While they do offer hope and commodities for its members, the way they reach out to its members is far too similar to how Real Life cults operate.
Boris Cliff in spades. He's an older man who works closely with Nazuna and isn't afraid to get up close and physically touch her. This level of creepyness is something that Michiru constantly warns Nazuna about during their first encounter with him and it takes her a while to believe her. And that's not even mentioning how he turns into an obsessive literal monster in the final episode.
The Nirvasyl Syndrome. It causes the affected to go through intense Body Horror and completely lose themselves until they're either tranquilized or killed. And the only (as of yet) known cure is to lose their beastmen-powers and become human. Once you have it, you literally cannot go back to your old life.
On a related note: Alan Sylvasta's speech about how the potential to get Nirvasyl Syndrome and run amok is inherently part of a beastman's DNA and that erasing their beastman-side is the only way to cure it sounds dangerously close to eugenics. You know, that pseudo-science the nazis used to justify their mass-murder of minorities? Driven home with the reveal that he is a "purebred" beastman who views the others as inferior lesser hybrids. However, it turns out he is not so different as he nearly succumbs to Nirvasyl Syndrome himself despite his purebred heritage, only to be saved by Shirou and Michiru; the very type of beastmen he swore to erase. So anyone can fall victim.
