The name "Anima City" sounds a lot like animosity which means strong hostility. A fitting name for a city where it's citizens are always at each other's throats for the sake of survival.
Michiru is a lot less animal looking than other Beastmen. She is a tanuki with transformative powers, she's probably making herself look more human subconsciously.
Around the time Shirou locks Michiru in a closet in his office, Barbara Rose, the Mayor of Anima City, comes to visit. Here, Michiru attempts twice to get the mayor's attention by screaming for help at the top of her lungs. The second time, she seems to gain a bird's beak when she screams. Although, for comedy purposes, this may seem like a simple visual exaggeration of how loud she's screaming (as what is sometimes done in anime with other faces/animal facial features), there's also a foreshadowing that Michiru is not a normal beastman, as she gains and switches between several other animal traits throughout the season, and this particular instance can go unnoticed unless you are keeping it in mind on a second watch.
Shirou is shown eating the safety charm Melissa Horner made for him so that Ginrou can protect him. Given the reveal of Shirou being Ginrou himself, he was accepting her offering.
The first time we see Nirvasyl Syndrome it's on a rhino beastman, but with time he grows a second horn and another pair of arms, becoming more insect-like. He went from a Rhinocerous to a Rhinoceros beetle.
Alan displays mental instability and aggressiveness. Anyone who knows anything about 'pure-breed' in canines or humans know that the practice is essentially inbreeding and the cause of multiple physical and mental problems.
Marie's unusual degree of helpfulness (despite the "service charges") toward Michiru makes perfect sense: She sees a fellow social outsider fighting to get her identity recognized.
Michiru is a tanuki beastman and Nazuna is a fox beastman and both have similar transformation powers. In Japanese folklore, both tanuki and foxes (kitsune) are known for tricking and fooling others with their transformation abilities
Lizardman conspiracies are real in the BNA universe, albeit not with lizards.
Michiru using her tail as a crash cushion and a shield on several occasions gets infinitely funnier when you remember that tanukis in mythology really did do that - only they used their balls for it. Since Michiru is a girl, that naturally isn't an option for her.
In episode 2 Shirou refuses to let himself get checked at the hospital after he shields Michiru from a skyscraper and claims he'll be fine, despite bleeding profusely and almost falling over from the pain when he tries to walk away. It seems like pure stubbornness at first. But later on it's revealed that he's a Physical God with a Healing Factor. It's supposed to be a secret, so it makes sense he wouldn't want to stay at the hospital where doctors might ask uncomfortable questions about him healing so fast.
Additionally, the hospital is run by Sylvasta Pharamceuticals, whom Shirou is already suspicious of.
Shirou's casual sexist comment in "Rabbit Town" is more understandable when it's later revealed that he's over a thousand years old. Of course he would have some outdated views.
Fridge Logic
Animacity was founded as a safe place for beastmen. ... they tend to stay in a human disguise most of the time anyway. This gets even stranger considering Michiru, who spends much of the series wanting to get rid of her animal form, but ends up opting to stay in that form for pretty much the entire series (even after she figures out how to switch back to human form at will).
There are many cases where characters switch between human and animal forms whenever they're out of view, suggesting this could be a result of animator preference.
It's not expanded on much aside from Pinga mentioning the restrictions that come with Beastmen getting 'human' rights, but it's possible to read their preference for staying human as a form of assimilation, especially since one of the original goals of Anima City appears to be assuring the humans that beastmen can be 'civilized'
Michiru also mentions that maintaining her human form feels like "walking in heels", so it seems to take a conscious effort, whereas her tanuki form is the default,although Nazuna does not seem to have this issue possibly as her result of her training under Boris.
Another possibility is that most use their human forms as a way to level the playing field and hide their capabilities all at once. If both parties are in their human forms for amiable encounters (like the Horners), it makes them less threatening and more even with the person they're taking to (both parties human, instead of, say, a bear and a bird). If the situation is confrontational, it's a benefit to hide one's beast form so that the other person doesn't know what they're dealing with (say an attempted mugging going away when the would be victim is something like a rhino or similarly powerful beast, or a kidnapper only revealing they're something like a crocodile in order to force compliance, using the human guise to create a false security)
Something else to consider may be universal accomodations. Trying to design a city with amenities accessible to the full spectrum of Beastmen would be difficult to impossible (having to accommodate for things like different limb structures (Nina and Pingua), size considerations for things like antlers or tails, heightened sensory inputs (Shiro, Owls, etc), etc), so most Beastmen stay in human form as a matter of convenience and comfort (imagine, for example, trying to get through a door as a 12+ point buck, or being able to smell everything around you at high acuity).
