John Watson
Voiced by Yoshimasa Hosoya (JP), Jason Liebrecht (EN)
Friday/Noble Savage 007
Voiced by Ayumu Murase(JP), Todd Haberkorn (EN)
Hadaly Lilith/Irene Adler
Voiced by Kana Hanazawa (JP), Morgan Garrett (EN)
Frederick Burnaby
Voiced by Taiten Kusunoki (JP), J. Michael Tatum (EN)
Nikolai Krasotkin
Voiced by Daiki Yamashita (JP), Micah Solusod (EN)
