Author's Saving Throw: Franquin kept the rights to the character of the Marsupilami, which means the animal disappeared from the comic after his run (apart from one Fournier comic and some allusions under Tome & Janry) with no explanation. In the comic Wrath of the Marsupilami, written after Dupuis recovered the rights to the character, its absence is finally explained by having Zantafio using the Zorg-Ray on Spirou, Fantasio and the Count to have them returning the Marsupilami to its native Palumbia, then forgetting everything about the animal and flying into a rage every time somebody mentions it. The Marsupilami is rather enraged about it, but eventually makes up with them before deciding to remain in Palumbia.
Creator Breakdown: Franquin in the middle of QRN sur Bretzelburg. His "last" album, Panade à Champignac, can either be seen as an affective goodbye to the series... or as a big "Fuck you, I'm going to work on Gaston Lagaffe instead".
Morvan & Munuera tried to integrate elements from all their predecessors into their run (including Rob-Vel and Fournier), but unfortunately for them many fans wrote off the series after the departure of Tome & Janry.
An episode of the second animated series has Zorglub disguise himself as Fantasio and take his place. Zorglub!Fantasio, in contrast to real Fantasio's open dislike, engages in a more joking, flirty antagonism, which Seccotine is happy to play along with — though after the jig is up, she does note that she should have suspected something.
Taken out of context: Fantasio wakes up, apparently in the same bed as Spirou. He's covered in a whitish dripping liquid. He shouts "The condom! We forgot the condom!" (capote means both hood and condom)
The context: Fantasio and Spirou are sleeping in a castle ruin, in two separate beds. They used pieces of tarpaulin to keep themselves from the rain, except the one above Fantasio suddenly ripped and unloaded buckets of water on him. He wakes up shouting "The hood! We forgot the hood!" (on the car, to protect it from rain)
It should be noted that the example given is from the series "Spirou de...", which is basically a series of adventures unrelated to the canon universe... So this isn't exactly the best example to show how the Ho Yay is still alive and kicking...
Zorglub, even before his Heel–Face Turn. Also the whole point of Le Réveil du Z, where Zorglub's successor only manages to recreate The Theme Park Version of the original's vision.
Let's not forget Vito "La Déveine" Cortizone, a powerful mafia don who eventually is somehow deported through the little rural town of Champignac with nearly no security.
The Triangle went from "globe-spanning barely competent criminal organisation" in Du Glucose for Noémie to "half a dozen idiots who can't even operate their secret lair's traps correctly" in L'Abbaye Truquée, mainly because they lost most of their competent members in previously failed operations told between Glucose and Abbaye.