WARNING: Only spoilers for Seasons 4 and 5 will be whited out.
Actor Role Confusion: The intense hatred for Skyler ended up spreading to her actor, with many people (particularly on Twitter) openly stating they would attack Anna Gunn if they met her in real life. An article by Gunn revealed she even received death threats by idiotic fans who couldn't separate her from her character.
In the years since Mr. Show, Odenkirk's acting career had taken a bit of a back seat to his career as the producer of shows like Tim and Eric Awesome Show, Great Job! and Tom Goes To The Mayor. Now as the series winds down his acting profile has been raised considerably and the 2013-14 season will see him head up a Saul Goodman spin-off, titled 'Better Call Saul,' a new sketch comedy show and supporting roles in FX's Fargo miniseries and the Alexander Payne film Nebraska.
Jonathan Banks was previously well known for costarring in the TV series Wiseguy in the 80s and had mostly done low profile parts since. His role as Mike netted him an Emmy nomination and opened the door for a series of parts in high profile movies and a season long guest arc on Community.
Cast Showoff: Skinny Pete's actor is actually a very skilled pianist, which he demonstrates in one episode.
Breaking Bad might not show Albuquerque in the best light, but the place to pass though on the way to Santa Fe (and where Bugs Bunny keeps making a wrong turn) has reaped a substantial tourist benefit from the show's popularity. The Visitor's Bureau has a page dedicated to all the related tourist information.
"The Candy Lady", the sweet-maker who produces the blue-dyed rock sugar that appears as Walt's product in the show is also making a mint selling bags of it, especially after Bryan Cranston gave some to David Letterman on his show.
Generally speaking, any song that gets featured on the show is bound to get a rise in popularity. The biggest one is 'Baby Blue' by 'Badfinger,' used in the final scene of the final episode. After the show, online streaming of the song increased by 9000%.
Dawson Casting: Inverted at first with RJ Mitte who was 15 years old playing 16 year old Walt Jr. in Season 1. Eventually played straight as the series progressed. A minor inversion also applies to Betsy Brandt, whose character Marie is considered to be in her late 30s, but was 31 when the show started airing.
Disabled Character, Disabled Actor: RJ Mitte (Walt Jr.) has mild cerebral palsy in real life. Walt Jr. was conceived from the start as having it, and Mitte had to learn to walk with crutches and speak less clearly to portray the level of affectation that the show's creator had in mind.
Dyeing for Your Art: Bryan Cranston lost weight and shaved his head to play Walter. RJ Mitte (Walt Jr.) also quit taking physical therapy for Cerebral Palsy so that it would regress enough to convincingly play the part of someone who needed crutches to walk and had slurred speech.
Executive Meddling: A rare positive example. Walt was initially supposed to murder Jane rather than letting her die; either by injecting a second dose of heroin or deliberately pushing her onto her back to make her choke to death. Executives (and most fans) believed that the change was for the better, as it was far too abrupt a change in character so early on.
The main state prosecutor in the penultimate episode is Steven Russell's snooping colleague in I Love You Phillip Morris.note The one who figures out he's moving company funds to skim interest, and who later turns out to be a juror who recognizes him as a wanted felon.
On Aug. 16, 2012, the Tuscaloosa County (Ala.) Sheriff's Office named a new Most Wanted Fugitive. That person? Accused meth cook Walter White. (Not the hero of this show, but this guy.)
Mean Character, Nice Actor: Needless to say, the show's assorted homicidal lunatics, ruthless drug barons and other unpleasant people are much friendlier in real life. Particularly notable are:
Jesse Plemons plays Todd, a creepy neo-Nazi psychopath who murders a child in cold blood, tortures Jesse, kills Andrea, and threatens Walt's family. In Real Life, Jesse is a country/bluegrass songwriter.
The Cousins are almost robotic hitmen who kill without mercy or hesitation, even if their victims don't need to die. Vince Gilligan has described Daniel and Luis Moncada, the brothers who play them, as "a joy to be around".
Krazy-8 was originally scripted to die in the first episode of the series, but the crew so loved his actor, Maximino Arciniega, and so loved working with him that Krazy-8's story was extended for a couple more episodes, and Gus' "brother" in cooking meth was named after him.
Bryan Cranston is such a nice guy that when Betsy Brandt (Marie) had to say "Why don't you just kill yourself?" to his character in a scene, she physically hurt afterward and immediately had to hug him after they finished filming the scene.
Gustavo Fring is one of the most terrifying villains in television history. However, his actor, Giancarlo Esposito, is, by all accounts, an incredibly easy-going and sweet person.
A number of interviews with Vince Gilligan have said that he's remarkably affable and gentlemanly in person for the man who created such a dark and brutal world.
Uncle Jack is the leader of a gang of Neo-Nazis, and one of the most despicable villains in the series. His actor, Michael Bowen, is a well-spoken Method actor and father of four.
Walter White is Hal from Malcolm in the Middle (which is funny, considering that Malcolm... had one episode where Hal worries that he may have cancer, another where Hal is busted on drug charges, and a flashback where Hal is bald from a chemistry kit accident), if he left his wife and kids and took several levels in Badass.
The leader in Jesse's addiction recovery group is an Expy of Tobias Beecher. They both suffered from debilitating addictions that ended with an innocent girl run over by a car. Also, he's Justified's resident nutjob, Mr. Wynn Duffy!
Another Justified regular is Tucker's friend - who is also resident idiot Dewey Crowe on that show.
Landry now works for Walt. He's a lot less upset over murdering someone this time around.
Max Cherry has gone from tracking criminals to hiding them.note In the penultimate episode, he serves as the (eventual) face of Saul's "make people disappear" guy.
Star-Making Role: Aaron Paul went from a bit actor to being a two-time Emmy winner and one of the biggest stars on television with his portrayal of Jesse Pinkman.
The Other Darrin: Holly White was played by three different actresses over the course of the series.
Throw It In: In a late scene of "Ozymandias", Walt was supposed to just stare at Holly before deciding that he had to return her. Luckily the mother of Holly's actress was standing nearby, prompting the girl to cry for "Mama" repeatedly. Bryan Cranston worked with it, creating a far more powerful scene.
Vindicated by Reruns/Viral Marketing: The show is being held as a huge example of the impact internet streaming can have on a show. While it became a massive critical success very quickly, it always struggled in the ratings until its last eight episodes. The show took five years to go from under a million to 2 million viewers, only to jump to 10 million and become an internet phenomenon by its final episode a year later, thanks to excellent word of mouth and Netflix, seeing the show go out in a blaze of glory, both critically and commercially.
What Could Have Been: Learn anything about the issues this show has faced that caused radical plot rewrites, and marvel that it turned out so well. For starters, if the first season hadn't been cut short by the writers' strike, Jesse would have been killed at the end of it.
Raymond Cruz, the actor who played Tuco, asked to be written out of the show because he didn't feel comfortable playing such a violent character.
Vince Gilligan originally envisioned the show as being only four seasons long. It's possible that the actor playing Tuco deciding to leave earlier than expected made the writers have to build up to a new villain thus making the story longer than originally planned.
Hector Salamanca was originally planned as the villain for Season 3, and Gus Fring would never have existed if Tuco's actor hadn't resigned.
Walt was originally supposed to purposefully turn Jane on her back to ensure her death, as opposed to just letting her die but the studio and Bryan Cranston both disagreed with it.
Earlier versions of the scene had Walt kill her by injecting her with an extra dose of heroin.
While Bryan Cranston was always Vince Gilligan's first choice for the role of Walt, AMC initially offered the role to John Cusack and Matthew Broderick. It wasn't until they turned it down that Cranston finally got the part.
Breaking Bad was originally planned to be set in San Bernardino, California, but Albuquerque's incentives for filmmakers were such a big draw that the show relocated there.
Jesse was originally supposed to die in Season 1, and even after the writers' strike cut the season short, Jesse was originally going to be killed by Tuco "A No-Rough-Stuff Type of Deal", the Season 1 finale. No-Doze was killed off instead because Vince Gilligan realized how much potential Aaron Paul had for the role.
Jesse's character was originally named Marion Dupree, and Hank's last name was initially Weld.
Writing by the Seat of Your Pants: Every season with the exception of the second, which Vince Gilligan has said was very stressful. Notably, the Cold Open of "Live Free Or Die" was written without them knowing what the M60 would be used for.
"Face Off" feels a lot like a Series Fauxnalewith the deaths of Gus and Hector, and the ambiguity of whether Walt will stay in the meth trade because the writers didn't know at the time whether the series would get a fifth season.