Whateley Universe example: Don Sebastiano, after ruling the campus for a year, got his comeuppance when his two mindslaves were freed from their magical Mind Rape. He came back from a humiliation and dunking (in the middle of winter in New Hampshire) and thought Cavalier and Skybolt were still victims. The only thing that would have been worse is if all the dorm residents who stood around and watched had thought to get photos. Then, while in the hospital, his fellow Alphas came by and laughed at his medical charts: the lamp base that had to be removed from his lower colon was a big hit.
There's another fine example in Tansy 'Solange' Walcutt, who seems to exist solely for the purpose of a Humiliation Conga. She was doing perfectly well as the Don's second - right up until she made the mistake of attacking one of the protagonists. Her downfall since then has been... protracted, even if most of it is getting hoist by her own petard and refusing to learn.
Anti Villian example, in Doctor Horrible's Sing Along Blog Dr. Horrible just humiliates Captain Hammer thoroughly instead of killing him. It might have been worse than what he was planning, because Captain Hammer has shown himself to be incredibly egotistical and narcissistic, so having everyone pay more attention to Dr. Horrible, his arch-nemesis would be pretty mind-crushing.
Red vs. Blue: When Tex is reawakened... She takesonEVERYONE. The battle is thoroughly humiliating for the Reds and Blue. There's a reason that episode is called "This one goes to eleven"...
The Nostalgia Critic gets put through one hell of a conga at the end of Kickassia. After getting firebombed in his garden and fleeing for his life (with a girly scream), Critic is cornered in his own base and learns that his subjects have turned against him—and they're being aided by the traitor he had banished. Film Brain (who has been acting as Critic's personal Yes Man) tells him to his face that he hates his guts, while Phelous uses Critic's habit of stealing his ideas to trick him into literally inviting the group to kick his ass. Ask That Guy shows up, making Critic think he's been reprieved, only to happily leave once he gets in his obligatory "cameo appearance". The team beats Critic within an inch of his life, stripping him of his presidential hat and authority, which they then fight over with his second-in-command (who admits that she only took the job so she could murder him and claim the presidency for herself). In desperation, Critic threatens to kill himself and everyone else with the dynamite he installed under the base; he dramatically pushes the detonator...and nothing happens, because Cinema Snob disabled the explosives (after he was banished, no less). The group resumes beating Critic to a pulp (ruining his M. Bison costume in the process), and then forces him to return the country to President Kevin Baugh—with the admission that he couldn't handle the job. And in the end, he doesn't even get the rocket chair he wanted.
Xoanon's novelization takes the humiliation several steps further: Santa Christcalls out instructions on how to kick Critic's ass as he leaves; President Baugh gets to keep the rocket chair (which arrived after Critic's departure) for his own use; and several months after the fact, Baugh sends Critic a letter imploring him to learn a lesson in humility—with the battered, moth-eaten M. Bison costume enclosed.
Proton Jon gets this in The Runaway Guys's LP of the Mario Party 1 board Yoshi's Tropical Island. In one turn, he gets a poison mushroom, gets warped back a few spaces, and then Luigi and Yoshi (the former a CPU, the latter Nintendo Capri Sun) both get a regular mushroom from the same item space. All punctuated by him yelling "GAAAAAME!"
