Space Con
- Role Reprise:
- George Lowe returns to voice Space Ghost for the first time since the character's 2011 interview with Tommy Wiseau.
- Likewise, Andy Merrill voices Brak for the first time since the 2012 Cartoon Planet revival.
- The Other Darrin: The death of Clay Martin Croker in 2016 meant that Zorak and Moltar were recast with Jim Conroy and Bernado de Paula, respectively.