- Deleted Scene: An alternate introduction for Dr. Lupin had him entering the hospital dressed as the Grim Reaper.
- Playing Against Type: Jessica Alba is an evil, murderous gold-digger.
- The Shelf of Movie Languishment: Was shot in 2005, but not released until 2007 due to numerous delays by The Weinstein Company.
- What Could Have Been:
- Hayden Christensen replaced Jared Leto in the role of Clay.
- Jessica Alba replaced Kate Bosworth in the role of Sam due to Bosworth dropping out to shoot Superman Returns.
- Helen Mirren and Sigourney Weaver were both considered at one point to play Lilith.
- Working Title: Autops-me.
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