- Damas' death scene and Veger's following Moral Event Horizon moment in Jak 3: Wastelander.
- It certainly didn't help that Damas had unknowingly revealed just before his death that he was Jak's father.
- Also the point in Jak II where you're defending the "sacred site" in Dead Town, and when you finally finish off al the enemies and get to it, both you, Jak and Daxter realize that it's Samos' Hut, so instead of traveling through space, you actually went far into the future. And then it hits you that everyone and everything you knew from the first game (aside from Samos and Keira, obviously) is dead.
- In Jak X, When Jak catches up to Mizo and takes back the antidote needed to save him and his friends from Krew's poison, Mizo tries warning that Krew's daughter, Rayn, is going to backstab them. Jak just decides to leave him to die in his car's explosion, not without Mizo telling him he has a knack for leaving people to die, Jak says he's used to it. This was the same teen who from the first game seemed like he was having the time of his life adventuring, now he's so jaded to the fact that, yeah he's killed before, that it doesn't even phase him as much as some would think.
Tear Jerker / Jak and Daxter