- In the novel, Rosemary finds that during her pregnancy, putting even a tiny bit of salt on her food makes her so nauseated that she can't eat it. Salt is known as a symbol of good and protection against demons and other evil supernatural forces in many of the world's religious traditions, including Christianity. This may also be why eating the chicken heart makes her sick when other raw meat does not. Chickens are traditionally regarded as symbols of goodness and the Resurrection, and their presence repels demons.
- The miniseries debuts on May 11, Mother's Day.
- The Antichrist is born on June 25 - exactly the opposite of Christmas - in 1966. His birth is honored as "The Year One," much like the year of Jesus' birth. Jesus' ministry is believed to have ended when he was 33. The Antichrist's 33rd year will be the year 2000 - which many people thought would be the end of the world, or the dawn of a new world order.
- A novel with a major character named Roman Castevet goes on to have a film adaptation directed by Roman Polanski and co-starring John Cassavetes. Polanski even mentioned this to Ira Levin and proposed that the name might've been an unconscious Shout-Out, but Levin denied it.
- As a modern viewer the utter lack of power Rosemary has is shocking. She runs away and finds another doctor at one point begging for help. He in turn calls her husband and doctor, the ones she claims are hurting her, to come and get her and take her home! Everywhere she turns for help she's seen as just another hysterical female made worst by her pregnancy. She's dismissed and treated like a child by almost everyone but her fellow young women who are pulled away from her by those that control her and them. It's horrifying for the modern viewer.
- Minnie telling Rosemary at the end that Satan chose her to give birth to the Antichrist: was that just an off-the-cuff attempt to reassure Rosemary and calm her down? Or did she mean that literally—Satan rejected Terry and somehow knew about Rosemary, then acted as The Chessmaster to manipulate her into the clutches of the Castevets?