The Courier can use their desert skills, Disciplines, or social abilities to help lead a massive jail break at a migrant camp being used as a blood farm. If you play your cards right then you can help literally hundreds of humans escape a Fate Worse than Death. This notably can restore your Humanity to maximum, resulting in a Heel–Face Turn if you choose to play it that way.
When you first meet Nilay, the obnoxious Ghoul at the migrant camp, if you have access to, and use the Presence Discipline, and proceed to threaten them, not only do they get cowed into submission, so does EVERYBODY ELSE in the camp. Even the heavily armed guards throughout the camp, are quaking in their boots around you. One even APOLOGIZES for how Nilay was acting, then proceeds to give you a map, and detailed directions to Olivcrona's tent, with all the tone, and attitude of a store employee, instead of a grizzled soldier/militamen. Even Olivcrona's ghouls guarding her tent are nervous around you. The only two who aren't affected are Olivcrona herself who you only meet after it wears off, and her dog which is completely mind-controlled by Animalism. A moment of vampire badassery and awesomeness at its finest.
The Courier can successfully fight the Lampago, a Pre-Colonial Gangrel, to a standstill or perhaps even slay the monster. This despite the fact you are only a Neonate with some pawn shop purchased weapons. Doubly so if the Courier is trying to protect a group of innocent researchers.
The Courier can also have a Villain Team-Up with Lettow and Julian to slay the Reremouse, a Nosferatu methuselah that threatens the Masquerade.
You can deliver a package to a small plane taking off of a runway while being chased by the Second Inquisition. This can include throwing the package on it while being shot at repeatedly.
There are multiple car chases throughout the game potentially with the Courier ending up re-enacting Smokey and the Bandit with the Second Inquisition. Even more badass, potentially, is you use your knowledge of stealth and the local environment to never be found.
In the final confrontation against Donati (in the Camarilla ending of the game), a Courier with maxed-out Dominate can simply command the final boss to drop her weapon. Donati only has time to scream when she realizes she's obeyed the command before Lettow shapeshifts and kills her in glorious fashion.
The Blood Sorcery and Protean Disciplines can have some pretty cool effects, and uses in the game. However, one method you can obtain both with, can be rather awe-inspiring as well. Of special note is the Ministry vampire Eduoard, can also give you a rather unique method. He gives a book with 3 chests filled with ritual items. After reading the book, the Courier then "knows" a ritual to summon a spirit, that teaches you all of the spells of Blood Sorcery. As opposed to the Tremere Invidia Caul who simply gives you a pile of boring books to study, which eventually teaches the Courier Blood Sorcery. Also Eduoard's method of Protean, unlike the other version, lets the Courier transform into a GIGANTIC SNAKE, as well as elongate their fangs to secrete venom, like a snake. Say what you will about the Ministry, but their artifacts, rituals, and powers are nothing short of awesome in their own right.
Lettow
Despite being a Gangrel, Lettow manages to take over the Princedom of Tuscon, Arizona after a Civil War between the local Ventrue. And how did he kill the old Prince? With a crossbow made out of his Rolls and a massive stake he stole from the guy.
Lettow is a veteran of many wars and doesn't mind getting his hands dirty. He chooses to fight the Reremouse alongside Julian and attempts to blow it up with explosives.
Lettow outsmarts the Second Inquisition so they drop a hellfire missile on the building next door to the meeting he's having, alerting you to their presence.
Lettow's plan for the Second Inquisition luring them into the Viper and then using the secret passages to cut them to pieces. It results in the death of over a hundred hunters and the death of Agent Donati, possibly at his hands. The Second Inquisition is said to be crippled in the Southwest for decades.
Julian
Julian may be annoying and insufferable but he's undoubtedly a genius. He's picked up on what almost no other Kindred have in that The Masquerade is unsustainable and the only way to survive to the 22nd century is a "controlled crash" of the Masquerade where the undead reveal themselves on their own terms.
Julian can help you takeover a free hospital in order to make money hand over fist. It's just at the small cost of the Kindred and poor already being served there.
