History YMMV / OsmosisJones

* CompleteMonster: [[DiseasedName Thrax]] is a [[MonstrousGerms deadly virus]] who is [[FameThroughInfamy obsessed with infamy and making his name known in the medical books]]. To this end, Thrax infiltrates human after human and slowly kills them through an agonizing fever--one of his previous victims was a [[WouldHurtAChild little girl]] who "didn't like to wash her hands"--which comes with the consequence of killing both the human and every living organism inside of them. Upon invading the body of Francis "Frank" [=DiTorre=], Thrax [[EstablishingCharacterMoment introduces himself]] burning a cell unfortunate enough to cross him from the inside out whilst humming, and cuts clean through a local crime boss to cow his flunkies into serving him. Thrax sets about murdering whomever comes in his way and [[BadBoss burns his own flunkies to death]] after they suggest incubating, ultimately [[NearVillainVictory nearly succeeding]] in dooming Frank and gloating to hero Osmosis Jones that he intends on breaking his record on Frank's young daughter Shane.

* LauncherOfAThousandShips: [[EvilIsSexy Thrax]]. Fans tend to ship him with either [[FoeYay Ozzy]] or a SelfInsert, and many a {{Fanvid}} maker has made fan edits of him with just about any 2D animated female you can think of, the most popular choices being [[WesternAnimation/TheSwanPrincess Odette]] and [[WesternAnimation/SinbadLegendOfTheSevenSeas Eris]].

* LauncherOfAThousandShips: [[EvilIsSexy Thrax]]. Fans tend to ship him with either [[FoeYay Ozzy]] or a SelfInsert, and many a {{Fanvid}} maker has made fan edits of him with just about any 2D animated female you can think of, the most popular choices being [[WesternAnimation/TheSwanPrincess Odette]] and [[WesternAnimationSinbadLegendOfTheSevenSeas Eris]].

** Even among the film's detractor's, Leah Estrogen is seen as this for her honesty and caring attitude without being offensive.

* HoYay: Jones and Drix. ''I think I'd like to stay with Jones'' indeed.
** FoeYay: Ozzie and Thrax, especially this line from the latter - "You know what, Jones? You want this chain so bad, Big Daddy Thrax is gonna let you have it!"

* SoOkayItsAverage: The general consensus of the film if you exclude nostalgia.

** Frank eating the egg as it switches to the first animated portion of the movie taking place in Frank's mouth, as it was one of the scenes most prominently showcased in promotional material for the movie. This is in addition to how memorably disgusting the scene is, said egg having been previously ''in a monkey's mouth'' and then ''on the ground of the monkey cage''.

** Mayor Phlemming has received some notice that he resembles U.S. President Donald Trump in terms of personality, and his response to the COVID-19 pandemic where some claimed he tried to downplay the threat of the virus to prevent risk to his re-election and claimed he was doing it to prevent a nationwide panic. Which were the same reasons to why Phlemming refused to draw attention to Thrax in the City of Frank.
-->'''Drix''': Sir, he was a lethal virus! If we hadn't stopped him...\\
'''Ozzy''': We'd be fried eggs off of Frank's dead butt!\\
'''Phlemming''': Watch your mouth, kid. Talk like that could cause a panic!

** Mayor Phlemming has received some notice that he resembles U.S. President Donald Trump in terms of personality, and his response to the COVID-19 pandemic of where he tried to downplay the threat of the virus to prevent risk to his re-election and claimed he was doing it to prevent a nationwide panic. Which were the same reasons to why Phlemming refused to draw attention to Thrax in the City of Frank.

** Frank eating the egg as it switches to the first animated portion of the movie taking place in Frank's mouth.
** Thrax's monologue about wanting to break his record so he could have a place in the medical books.
*** His introduction is also quite noteworthy showing off [[KnightOfCerebus just how dark the movie gets]].
** The Zit sequence.

** Someone with Frank's habits and with the constant talk of how unhealthy he is should be a great deal more obese than Bill Murray.
** Then again, it's not uncommon at all for average weight people to live unhealthy lives.

** Mayor Phlemming has received some notice that he resembles U.S. President Donald Trump in terms of personality, and his response to the COVID-19 pandemic of where he tried to downplay the threat of the virus to prevent risk to his reelection and claimed he was doing it to prevent a nationwide panic. Which were the same reasons to why Phlemming refused to draw attention to Thrax in the City of Frank.

** Mayor Phlemming has received some notice that he resembles U.S. President Donald Trump in terms of personality, and his response to the COVID-19 pandemic of where he tried to downplay the threat of the virus to prevent risk to his reelection and claimed he was doing it to prevent a nationwide panic. Similar to why Phlemming refused to draw attention to Trax in the City of Frank.

** Mayor Phlemming has received some notice that he resembles U.S. President Donald Trump.

** Frank eating a Circus Peanut while trying to have a moment with his daughter about her mother passing away is such a pathetic sight that you can't help but laugh at it. It's often seen as a low point for Bill Murray, who's otherwise a fantastic actor.

** Thrax declaring that "Ebola is a case of ''dandruff'' compared to me!" is made somewhat funnier by the arrival of [=ZMapp=], Ebola's highly tentative cure. Could also be a FunnyAneurysmMoment after the Ebola 2014 break out. The subsequent 2019 Coronavirus outbreak also led to many jokes about the film.

** Frank eating food while trying to have a moment with his daughter about her mother passing away is such a pathetic sight that you can't help but laugh at it.

** Thrax declaring that "Ebola is a case of ''dandruff'' compared to me!" is made somewhat funnier by the arrival of [=ZMapp=], Ebola's highly tentative cure. Could also be a FunnyAneurysmMoment after the Ebola 2014 break out.

** '''''"HAI BABEH!"'''''"

* CultClassic: Generally regarded as a dud with too many unfinished or poorly-realized ideas, it otherwise has a decent fanbase of nostalgic millennials who love it for what it is. The fact that it's one of the only theatrical traditionally animated features from UsefulNotes/TheMillenniumAgeOfAnimation certainly helps.

* HarsherInHindsight:
** The movie building up Osmosis and Leah as a couple goes down the drain when you put the spin-off show into account where Osmosis and Drix are forced out of Frank and transferred to a different body.

** The entire movie can be considered this in light of the COVID-19 pandemic of 2020. Frank definitely doesn’t practice good social distancing (high-fiving a man after sneezing in the same hand, putting his bare foot on a restaurant table). Meanwhile, Ozzy’s warnings about Thrax are either not taken seriously or outright covered up until it’s almost too late, much like what happened with Chinese doctor Li Wenliang. Finally, Thrax’s M.O. is to cause mild symptoms before “making his move”, much like how COVID-19 starts with seemingly innocuous symptoms.
** The song "I Believe" by Music/RKelly makes for a pretty touching ending...until you find out he's currently serving time in prison for his accusations of sexually assaulting children.

* ValuesResonance: By 2020, with the Coronavirus pandemic around, Thrax is considered a purely relevant animated villain.

* DracoInLeatherPants: Thrax has a pair to go with that leather jacket.

* HarsherInHindsight: The movie building up Osmosis x Leah as a couple goes down the drain when you put the spin-off show into account where Osmosis and Drix are forced out of Frank and transferred to a different body.
** The entire movie can be considered this in light of Covid-19. Frank definitely doesn’t practice good social distancing (high-fiving a man after sneezing in the same hand, putting his bare foot on a restaurant table). Meanwhile, Ozzy’s warnings about Thrax are either not taken seriously or outright covered up until it’s almost too late, much like what happened with Chinese doctor Li Wenliang. Finally, Thrax’s M.O. is to cause mild symptoms before “making his move,” much like how Covid-19 starts with seemingly innocuous symptoms.