You look at some of this old animation and go, well, thatís a little bit odd looking. Why is Spider-Man on Doctor Doomís shoulders? Why does he seem to be hugging Green Goblin? And thatís where you could just come up with ideas and have fun with it.
—Cort Lane, Vice President of Marvel Animation Development & Production
Make a Wish: Sue wishes on a shooting star for peace on Earth, then asks Reed to make a wish. He wishes for more ice cream, prompting Sue to make him make a better wish. Reed then tells Sue he wishes she'd buy more ice cream.
Fortunately, the dedication to Boyd Kirkland at the end of episode 32 didn't get immediately followed by one of these videos. A tutorial about drawing Venom played in between to minimize mood whiplash.
Mundane Utility: Captain America asks Thor to spin his hammer, not because danger is approaching, but because Cap needs a breeze from the heat.
Mystery Box: Magneto makes Spidey choose between a Hawaiian cruise, or the prize behind the curtain. Spidey picks the latter, and gets trapped in an hourglass.
Naked People Are Funny: Bruce Banner calls out Iceman on not wearing a shirt or pants, so Iceman strains to justify this by claiming "science" proves that if he wore clothes, they would "freeze to death."
"Hulk don't like tan lines."
Nausea Fuel: In-universe, the bologna and sardine sandwiches that Sue makes even cause HERBIE to barf.
Not Quite Flight: Hulk can't fly, but he can jump great distances. Exactly how great conveniently varies depending on how far he needs to go.
Off Model: Lampshaded when The Wasp says she doesn't like Captain America replacing his blue mask with a red mask.
Oh Crap: Green Goblin insists to Spidey that he's not afraid to fly into the powerlines, but this quickly proves false.
Redundant Parody: The series tends to support John Byrne's dictum when trying to write a parody of the Fantastic Four: "I'm sorry, it's impossible to write parody Thing dialogue that doesn't sound like the real thing."
An early episode had a joke about Spidey being the only Spider-Friend without a flashy Transformation Sequence. The original show joked about this a few times.
Running Gag: Captain America's segements contain several short scenes that consist only of him performing stunts while saying something patriotic.
Tempting Fate: While Norman Osborn mixes chemicals, he says, "Just mixing up some chemicals, nothing can possibly go wrong" in a sing-song voice. An explosion subsequently occurs during his experiment, ruining his "entirely average face".
Toilet Humor: The "farts are funny" kind shows up from time to time. Best example is Jennifer Walters having flatulences while driving Bruce Banner... And then closing and locking all the windows.
Unmanly Secret: Doctor Doom plays with dolls of the Fantastic Four. He accidentally lets this slip to Reed when ranting about getting another cloak for his birthday, and also admits that he loves ponies.
Up to Eleven: After Bruce asks Rick to rate his breath on a scale of 1-10, with 10 being the smelliest, Rick gives him a score of 11. He proceeds to say it smells like Bruce ate a bag of the neighbors' garbage, but didn't swallow it.