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- Angel Sanctuary: Rosiel presumably went through this, though he's long gone by the time the story starts.
- In Claymore, the warriors can gain immense power by tapping into their Super-Powered Evil Side, but need to resist its temptations or go too deep in and become a monster themselves. Those who manage to pull themselves back from the very brink of going to the dark side and "Awakening" gain a boost in power and can tap their power more freely than the others.
- School-Live!: In truly horrific fashion. Megu-nee gets turned into a zombie protecting the kids. While she's clawing at that their door she shows a brief lapse of sentience and becomes horrified of what she's becoming. She locks herself away in the basement of the school so she wouldn't hurt the girls, though she later bites a character when they go down there and is Killed Off for Real by Miki.
- A chapter of Venus Versus Virus has a girl who has been attacked by a Virus coming to Lucia to ask for help with her sibling. She doesn't consciously remember the attack and just thinks a monster is stalking her brother. Subconsciously she knew she was becoming a Virus though and later she's shown trying to resist it. Lucia kills her before she can and she dies as her normal self. Lucia notes this is the first time she has heard a Virus resist automatically transforming.
- Bruce Banner is usually lucid enough before he turns into The Hulk to tell innocent people to get away and try to quell his anger before it's too late. On a very good day, he might succeed, only to be set off by an even bigger event.
- Doctor Curt Connors of Spider-Man, being another character influenced by Tragic Movie Monsters, has lots of scenes like this as he's turning into the Lizard. He failed in the worst way possible when he devoured his own son. Curt effectively died after that, leaving only the Lizard.
- Morbius the Living Vampire, though always visibly a monster, faces this trope psychologically when his bloodlust hits him at an inconvenient time.
- Pulled off quite nicely by Doctor Doom in Marvel Zombies. Doctor Doom, out of literally everyone in the Marvel Universe, is the only one who can remain himself permanently while infected through sheer willpower alone.
- Jack Russell, the titular werewolf in Werewolf by Night, often goes through this during full moon nights. He is capable of delaying his Involuntary Transformation for a little while, but the longer he does so, the angrier his werewolf self is when he inevitably does transform.
- BioShock: Right Place, Right Time, Wrong Guy: Mark goes through this after he's forced to take ADAM and use plasmids in other to survive. But fights the temptation to keep using more so as not to turn insane like the residents of Rapture.
- Children of an Elder God: The main characters gain powers when they kill Eldritch Abominations. However, their stolen powers are inherently foul and corrupting. So all of them feel dark urges and desires, and they struggle against them the whole time.
- The protagonist of An American Werewolf in London tries and fails. His dead friend recommends suicide as the only option.
- Inverted in X-Men: First Class, when Professor X tells Hank McCoy to "set the beast free." Here, the "Beast" is portrayed as natural instinct, rather than evil.
- Doc Oc pulls this in Spider-Man 2 at the very end, resisting his robotic arms.
Doctor Octavius: Listen to me now!
- 28 Days Later - at the road block. Bit of a tearjerker too.
- Johnny Blaze has this problem in Ghost Rider: Spirit of Vengeance. Since the Rider in this movie would kill for the pettiest sins, he constantly struggles against its influence with isolation or stolen meds.
- Sam Vimes is a rare case of someone who succeeds in keeping the beast locked inside. It's not an actual werewolf-like curse, but his darker nature that's always straining to be released.
- In Thud!, Vimes gets possessed by a vengeance demon. While he starts going on a rampage, he prevents himself from killing a squad of defenseless dwarves long enough for Angua to take him down. To show how awesome this is, it's noted that if he had done so for just a few seconds longer, his muscles would have torn themselves apart.
- Vimes also does it with the Gonne in Men at Arms, as opposed to Carrot who is The Immune.
- Otto Chriek and other vampires in the Uberwald Temperance Movement have forsworn drinking human blood, but often have to struggle to suppress their natural urges (they generally succeed by diverting the urge into some sort of addiction or hobby). Though if one cannot fulfill their new addiction they will go berserk.
- The Dresden Files:
- Red Court vampires don't turn into full-blooded vampires after being infected until they give in to hunger and lethally feed on a human being. Some half-bloods are known to have resisted the temptation for centuries.
- This has been a large part of Harry's life. After touching a one of the coins of the Blackened Denarius in Death Masks and until White Night, Harry has to deal with the temptations of a shadow of Lasciel in his mind all the time. In White Night particularly, we see him giving in without fully being aware of it until it's pointed out to him. From Cold Days onward, Harry has to deal with the the Mantle of the Winter Knight and its inherently violent impulses, which he is constantly having to fight down.
- Dillon Cole wrestles with his destructive urges in Scorpion Shards, gradually succumbing to them and unwittingly feeding and strengthening the otherworldly parasite corrupting him.
- The Hunger Games: In Mockingjay a hijacked Peeta spends a large section of the book fighting the urge to kill Katniss, asking the others to kill them, refusing to have handcuffs removed and using the pain of the too tightly wound cuffs to keep sane.
- In A Wolf In The Soul, this is played straight with regards to Greg's physical transformation - especially the one that begins to take place in front of his mother - but Greg keeps his human mind at all times except for during his out-of-body experiences.
- Journey to Chaos features this in mana mutation. Once the transformation has begun, it is impossible to stop. All one can do is prevent it from reaching the victim's mind. At that point, they become increasingly savage no matter how they try to hold on to their sanity. In Mana Mutation Menace, both Eric and Nolien struggle to cope with the changes it has brought on.
- Buffy the Vampire Slayer
- This trope plays out a number of times with Oz, a werewolf. Before his status is out in the open he tries to get Willow to leave without telling her why (fearing he's going to be killed after having overheard Buffy say she's going to off the werewolf when she finds it). Later, in "Beauty and the Beasts", he even tells her to get away from him after he's been locked up in a cage.
- Similarly, Angel is shown having to resist feeding on humans in the episode "Angel" where his vampiric nature is first revealed. Darla attempts to tempt him into feeding on a wounded Joyce.
- In the Doctor Who episode "The Pandorica Opens", Rory is unable to stop himself from shooting Amy when his programming as an Auton takes over; fortunately, both of them get better in time to help the Doctor save the universe.
- Forever Knight used this a lot, with Nick trying to resist losing control of himself and killing someone.
- In the Supernatural episode "Meet the New Boss", Castiel is about to be taken over by the Leviathans, and yells at Dean and Bobby to get away from him.
- The vampires in Vampire: The Masquerade literally have to resist the Beast, where "Beast" is a lore term for their compulsion to just let loose and feed upon any human within reach (usually breaking the masquerade in the process). To resist it, you have to pass Willpower checks every time the character experiences a particularly traumatic event, such as being exposed to fire or even sunlight. Having high Humanity score also helps. Fail one too many checks and your character turns into a mindless bloodsucker, though. In the spiritual successor, Vampire: The Requiem, the Beast is still present and at war with the Man. However, various vampire groups have developed ways to ease the struggle. The Ordo Dracul have a Coil of the Beast that makes the struggle simpler (at its final level, you can give in for an hour to defeat it for the rest of the night), and the bloodline known as the Kukufuuji have developed a discipline based on restraining it.
- Dungeons & Dragons 3.5 has this for some intelligent undead, describing the dark obsessions that affect their minds, like a wight's instinctive loathing for anything living or a mummy's monomania for guarding its burial site. Some undead have Horror Hungers that will slowly drive them insane if not indulged or resisted.
- General Pepper is infected with the Aparoid infection in Star Fox Assault, and has to be fought in a boss battle. The whole time, he tells Fox and crew to just finish him off, ending with "never thought I'd be fighting all of you" before the process takes him over completely.
- The second Osu! Tatakae! Ouendan game has the teenage werewolf Ooyama Garou try to avoid staring at round objects while on a date, as that is what triggers his transformation. Unlike most examples, this is played for comedy and his trigger are things like balloons, baseballs, and even the shiny bald head of his boss. Assuming the player wins the level, his girlfriend is totally unfazed by his werewolf form because she's a dog lover. And what sets him off at the end? Her eyes.
- In the worgen starting zone in World of Warcraft, you're sent to talk to this one guy and he growls at you to stay away, then loses control and attacks you, at which point a teammate of yours comes in and shoots him. You shrug off the resulting wound as 'probably nothing', and say nothing about it even when it starts festering and you're feeling quite ill.
- In Resident Evil: Code: Veronica, Steve Burnside becomes a hulking brute with an axe. After a bit of hack-and-slash, he manages to resist the murderous impulses of infection, at the cost of his life.
- The plot of the Flash game Don't Escape. The hero is a werewolf who realizes he's only got a few hours before the moon rises, and must try to restrain himself as best he can.
- In Melty Blood, Vampire Sion/Sion TATARI (Sion who had given in to her vampiric impulses) is a playable character. In contrast to regular Sion's collected and stoic composure, V. Sion/TATARI is more noticeably emotional in her speech - several of her pre-fight quotes are either screams of pain or halting pleas for whoever she's fighting to run away.
- In the same vein, vampires in The Kingfisher risk mindless blood frenzy if they don't drink blood regularly. This isn't the focus of the story so it doesn't come up much.
- Several times in BIONICLE. Most of the 2005 storyline revolves around The Toa Hordika wrestling with their Beast Man nature. Also, Lewa had to do this during the time he was possessed by a Krana.
- Happens several times in the Jackie Chan Adventures episode "The Lotus Temple," where a little girl is cursed to become a monstrous guardian for a magic temple whenever someone intrudes. Since she's very opposed hurting anyone, she does this near every time. The heroes manage to find a loophole (being invited doesn't count as intruding), and at one point she does manage to stop herself from going psycho long enough for them to use it. Later on, she's able to focus herself towards the real villain.