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- The Palmolive dish soap ads regularly feature a pair of hands. They were originally actual people's hands with animated eyes and hair, but are now animated completely.
- Another Palmolive ad had a family of hands arguing about who would get to do the dishes. There was even a dog, also played by an animated human hand.
- A car ad for Mazda had people's toes singing and tapping out the rhythm of a song because the car was so much fun to drive.
- A series of commercials for an allergy product during the late 1990s featured a disembodied human nose at their main character.
- Allergy commercials with giant talking noses; too many to describe.
- One disturbing '90s ad for low-cut jeans had a belly-button sing "I'm Coming Out".
- An infamous 90s Reebok advert went a bit further than this and showed a disembodied giant hairy belly chasing an athletic man through a city, mostly by gelatinous hopping, and culminating in a motorbike chase, while repeatedly shouting "Belly's gonna get ya!" You can view the madness here.
- An ad for an athlete's foot product has a claymation foot, still attached to its owner, catch fire, grow a pair of evil eyes, and charge at everyone nearby, roaring. Made even creepier by the commercial's combination of claymation and live-action footage.
- An antacid commercial featured an anthropomorphic stomach in a busted-up hotel room checking out of it to the tune of Heartbreak Hotel.
- This Coke Zero commercial, where the body parts themselves have decidedly non-human legs. And what kind of person has two tongues and one eye?
- Some Ballpark Franks commercials feature an arm emerging from a person's stomach representing their hunger, forcing the person to eat a hot dog using various levels of subtlety. "HUNGER GET WHAT HUNGER WANT"
- A California Milk Board's ad may be creepiest example of this trope: A woman in the kitchen suddenly flops out of sight behind the counter. Her skeleton stands up, absent of any other tissue. The woman's discarded, fully clothed and otherwise 'undamaged' flesh, just lies there on the floor... and when the woman's skeleton reassures the husband that she's just getting herself some milk, her eyes... roll... towards where the skeleton is standing now.
- A disturbing UK advert for an itch relief cream featured a talking patch of skin that sounded like a falsetto Bill Bailey, and attempted to urge the woman in the advert to give it "just one little scratch", which the woman did, but eventually screaming "Aaah! Not Eumavate!" when the cream was applied.
- Dr. Scholls has a wart remover commercial where the wart talks. It's disturbing as it sounds...
- There is an advert occasionally seen in Britain featuring faces made of hands talking about, oddly enough, Adult Learning courses or something similar. It does make slightly more sense in context; the tagline is "Our future. It's in our hands."
- There is a cell phone out whose selling point is that it has a full keyboard, enabling you to "text it how you say it." The commercial consists of various people's thumbs (with their faces on them, mind you) speaking as they type.
- An Australian Ad for Tooheys Extra Dry features a tongue which dislodges itself from its sleeping owner's mouth before wiggling itself to a party, where it dives into a bathtub of ice and bottles of beer, wraps itself around the Tooheys Extra Dry and drags it back to its owner who wakes up wondering why he has a bottle in his mouth.
- A vintage Alka-Seltzer ad had a man arguing with his stomach, just as if they were a bickering couple at a marriage counselor. (Note the stomach's voice: it's Gene Wilder.)
Stomach: . . . the way he stuffs himself at his mother's!Man: You always hated my mother!
- An ad for some sort of cough medicine features a talking hand wanting the person its attached to to take the medicine instead of coughing into it.
- Those Lectric Shave commercials where his beard hairs look exactly like him and look happy as they're being shaved away into oblivion.
- In a recent Tabasco Sauce ad, there are pepperonis with faces on them that sing about the sauce. There are two variations of this commercial. one with a sing-along subtitle on it, and one without.
- One of Old Spice's new "Odor Blocker body wash" commercials.
Spokesman: ...Its blocking power is as powerful as me!Voice: Yeah it is.Spokesman: Who said that? (arm grows out of right bicep, pointing at the left bicep) Was that my left bicep? No. It was my...Abs: (in previous voice) Ab-dominals.
- One ad campaign had a boy's stomach barge into his brain, interrupting whatever he happened to be thinking about, and loudly declaring "It's time for this boy to think about his hunger". This resulted in the boy's stomach grumbling (get it?) and him going and getting a pizza pocket.
- A series of ads for Summer's Eve cleanser had talking vaginas. Yes, it's very disturbing.
- The ad for an overactive bladder drug that features an an anthropomorphic bladder demanding to use the restroom again and again.
- A radio ad for a local tea store featured a person's taste buds arguing over what kind of tea they wanted.
- The final segment of the movie Everything You Always Wanted To Know About Sex (But Were Afraid To Ask), featuring Woody Allen as a sperm.
- Played for Laughs in The Goblins of Labyrinth, a Terry Jones/Brian Froud collaboration tie-in to the movie. One species of goblin has a detachable penis responsible for some very bizarre unions, and another specimen's heart has the ability to jump off its location on his back and scuttle off on its own. He actually gets significantly nicer when it's on holiday.
Live Action TV
- One episode of Red Dwarf featured Rimmer the hologram 'accidentally' having another dead crewmember's arm uploaded instead of his own. Hilarious fights ensue.
- In an episode of Scrubs, Carla sees Turk's mole talking to her.
- On an episode of It's Garry Shandling's Show, Garry failed the written portion of his driver's license renewal test. Upset with his brain for being so stupid, he hooks a camera up to his TV and points it into his head so he can see his brain. The screen reveals a fat guy (character actor Stuart Pankin) lying in a hammock, who berates Garry for not challenging him enough, and they make a deal with each other: Garry will stimulate his brain more, and the brain will work with him. While they have this conversation, other body parts come to visit the brain, including a short, bald man referred to as "Mr. P" (pancreas) and his larynx ( Dave Coulier), with whom he argues.
Larynx (Dave Coulier doing a spot-on Garry Shandling impression): Hi, Garry!Garry: Is that my voice? I don't sound like that!Larynx: Yes you do!
- In the night-time omnibus editions of UK soap Night and Day, the character Will Radcliffe is frequently spoken to by a voice emanating from just below his waist. 'Little Will', who speaks in a deep American accent, is solely preoccupied with matters sexual, as one might expect - but other characters are apparently unable to hear him.
- In the Clive Barker short story "The Body Politic," a pair of hands gains awareness and starts plotting against their unsuspecting owner. Body Horror ensues.
- "The Nose", a short story by Nikolai Gogol, is about a man whose nose flees and disguises itself as a human. It should be mentioned that the Russian name of the story, "Nos", is the Russian word for "dream" backwards. There's an opera adaptation of it.
- At least two Peanuts strips had various parts of Snoopy's body expressing opinions of their own—usually connected with jogging, which meant the feet said a lot. One of these strips ended when his heart commented, "Just remember, boys - if I go, we all go!" to which the feet remarked, "That's scary!" and another part said, "Shut up and keep jogging."
- Promethean: The Created has "pandorans", created when someone fails to make a complete artificial human and instead end up with a bunch of animated organs and limbs. They're fueled by the same energy source as Prometheans (who tend to leak power), so that they come to life when one comes near, but otherwise will become dormant and look like ordinary objects if they run out of energy.
- Pathfinder has several undead formed of animated body parts, including the Crawling Hand and the Isitoq, an eyeball that uses its tattered optic nerve as wings.
- Used in an extremely disturbing fashion in Dead Space with the Divider enemy, which explodes and then the body parts reanimate in an attempt to take over the protagonist's body in the most disturbing way possible.
- During the Old World Blues dlc for Fallout: New Vegas one of the final confrontations is with your own brain, which you must convince to rejoin you.
- The internal enemies in Mario & Luigi: Bowser's Inside Story are things like immune cells, which attack with a body check, and neurons, which attack by way of electric shocks.
- The Halloween Hack: Dearkhart and the Anxiety Attack enemies.
- Bigeye in Something Else. It's a giant eyeball and the pet of the Evil Guy. It is quite easy because it has no projectile attacks.
- Dwarf Fortress: Various severed body parts — including skin and hair — can be reanimated by Necromancers and clouds of gas in evil biomes. This wasn't initially intentional, but Toady decided to Throw It In on the grounds that it didn't actually make any less sense than animated skeletons.
- In Monster Pulse, this is practically the entire premise. A mysterious energy somehow "infects" people and brings a randomly-chosen body part or organ to life as a separate, autonomous being. Unlike most of the examples on this page, they don't have human-level intelligence; they can vocalize and understand orders, but are only a little bit smarter than a well-trained animal.
- Several of the patients in Awful Hospital, though they prefer the term "free-roaming unisystemic vessels:" Thanks to the metaphysics of the setting, an ambulatory stomach can spend its time digesting, even though it's as far removed from any mouth or oesophagus as a human in London might be from the stretch of Amazon rainforest that produced their last lungful of oxygen.
- In Team Fortress 2 #5: Old Wounds, Demo hallucinates that his liver, sick of his alcohol-soaked existence, is leaving him for good. It plays out like a breakup scene.
"Alright, heart, figure out what the liver did. Lungs, you guard my rectum. Liver ain't welcome here any more."
- SCP-1319 consists of a researcher's individual upper and lower halves who got fed up with each other and decided to split — literally. What's really bizarre about this example (besides the obvious) is that neither half of his body exhibits the personality of the original researcher; they're both entirely separate entities.
- Done in the cold open of an Arthur episode, where his organs wonder where his brain went.
- In a Robot Chicken sketch, William Shatner's toupee goes out and lives a second life as a James-Bond style secret agent while he sleeps. He still hasn't figured out where the medals keep coming from.
- Leela's singing Susan-Boil from the Futurama episode "Attack of the Killer App".
- Rocko's Modern Life:
- One particularly strange Gumby short (called "Gone Clayzy") showed Gumby accidentally managing to pop the signature slant on his head off after knocking it into himself after falling off a tower of blocks. Independent of the now unconscious Gumby, the slant comes to life and proceeds to torment Prickle for a while until Prickle manages to reattach it to Gumby's head. And even after that, the slant comes to life one more time to give a brief Evil Laugh, to Gumby's confusion.
- Alien hand syndrome is a real life phenomenon where a person's hand appears to take on its own personality separate from conscious control. It can happen to people who have had brain surgery.