"Merciless" is the best word to describe the manner in which Exterminatus Now applies this trope, usually while subverting or justifying the trope being lampshaded. See Team Pet and The Smurfette Principle.
Pretty much any comic by S. Sakurai (Muertitos, Gorgeous Princess Creamy Beamy, Intragalactic) will be so crawling with lampshade hangings that choosing specific examples would be pretty hard.
Torg:Nothing can save us now! Zoe: What was that about? Torg: It's a classic cliché! In this type of situation, when someone says "Nothing can save us now," it's followed by someone showing up to save us. Zoe: You mean like "It can't get any worse"? K'z'k the Soul Collector:(suddenly appears) Hi kids!
Riff: A dynamic character with an ability to survive certain death, and a questionable death scene leaving no corpse? Face it, we'll never see her again!
Pee-Jee: How'd he get into your ice cream? That makes no sense. Davan: He's a 30+ year old pudding cat who can travel through drains but this is where your ability to believe is gonna be taxed?
And continued on:
Pee-Jee: Even so, there's a point where reality dictates— Davan: How'd that woman at your job die again? (fact: she was eaten by a ceiling alligator) Pee-Jee: ... this ice cream could use sprinkles.
And again:
Pee-Jee: Goddamnit! Why does everything revolve around sex around here?
Davan: ...bad writing...
Pee-Jee: Huh?
Davan: I'm sorry, I'm just reading John Grisham for the first time. This writing is awful.
In Sheldon: Arthur, a talking duck, says to the non-talking animals that, in a piece of fiction, "If one animal talks, they all gotta talk. You gotta keep it consistent."
Dark Legacy Comicsasks, "What do you think this is, some kind of badly written melodrama?!"
Often done in Chrono Redux in part to make fun of the comic itself, but also to make fun of the game "Chrono Trigger" when these sorts of things happens in the game. These are usually brought up by Chrono in internal monologues because he's mute.
Antimony: You - you're trying to summon it? But it's very dangerous! Student 1: Ah, don't worry! Student 2: It prob'ly looks mean but turns out ta be a nice guy! Student 3: Yeah, dat always hap- [CRASH]
Spacetrawler: The narrative regularly juggles three or four subplots, often timing the transitions between subplots just in time for gratuitous cliffhangers. There's also a Framing Device that Nogg is telling the entire story to Mr. Zorilla—and Mr. Zorilla eventually gets just as ticked about these shifts as the readers do. On this page, just as a major mystery about spacetrawler construction is about to be cleared up...
Mr. Zorilla: You're going to change to another storyline aren't you. Nogg: Meanwhile, back in Kppfing. Mr. Zorilla: I hate you. [On the next page, Mr. Zorilla has forced Nogg out of the car.] Nogg: Okay okay! I'll continue telling you about how spacetrawlers are made. Mr. Zorilla: Alright. You can get back in.
Homestuck is utterly rife with visual and verbal callbacks. Late in Act 5, Doc Scratch calls attention to the fact that these keep happening, and names the phenomenon "circumstantial simultaneity" (as opposed to mere temporal simultaneity). Then, in Act 6, Dirk Strider lampshades it again:
TT: I feel like you've said something like that before. TT: Different statements, but in that exact syntax. [...] TT: That actually sounds familiar too. TT: Are you sure you haven't said something like that before?