- Dueling-Stars Movie: Vince Vaughn vs. Jennifer Aniston, especially after they became a couple in real life while doing this film.
- Romance on the Set: Vaughn and Aniston became a couple in real life while doing this film.
- Separated-at-Birth Casting: Vince Vaughn and Vincent D'Onofrio have been mistaken for each other for years, so it naturally made sense to cast them as brothers in this film.
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