Sly and the Gang go to Haiti to take down Mz. Ruby, the Chief Mystic of the Fiendish Five, whose trying to raise an army of zombies to invade Mexico.
- Arc Villain: Mz. Ruby.
- Beast in the Maze: Mz. Ruby's giant snake, which is contained in a magically sealed area. When Sly had to traverse the swamp it resided in, the final third of the level involved him needing to keep ahead of it once it appeared onscreen.
- Bubblegloop Swamp: The mission is a completely straight example.
- Hollywood Voodoo: Raising/speaking with the dead? Check. Skulls and bubbling cauldrons? Check. All set within a grisly looking quagmire? Check.