The Sentinel may refer to:
- The 1977 horror film The Sentinel.
- The 2006 action film The Sentinel.
- The TV series The Sentinel.
- An Arthur C. Clarke short story, that is the inspiration for 2001: A Space Odyssey.
- A horror novel by Jeffrey Konvitz.
- A mid-80s computer game (known as "The Sentry" in the USA).