- Why didn't Dr Ogden's sister or Murdoch's father or half brother show up for their wedding?
- Word of God is that Ruby was out of the country, and Murdoch's relationship with his father is strained at best, and virtually non-existent with Jasper.
- Why didn't Murdoch tell his sister about their half brother? Then again, how does one broach that subject to one's little sister who's also a nun?
- In "Blast of Silence", Walter Pike was driven to madness because of all the noises of industrializing Toronto. Why didn't he just move?
- Because he was driven to madness.
- In "The Murdoch Trap", Gillies is revealed to have set up a trap that Darcy accidentally triggered and got shot, while he was pretending to be the driver. Yet he was explicitly stated to be seen entering the house ten minutes before the shot was fired? How the hell was he in two places at once? And how did he set up the death trap in Darcy's house?
- In "Raised on Robbery", the baby Roland is described as being nine months old, and Murdoch mentions that it's August (since he finds it odd that the Inspector is wearing a scarf). Then, in "Wild Child", characters are wearing winter clothing, and four other episodes/cases have happened in between. But Roland is still described as nine months old, and his dead mother's body is only now getting an autopsy, even though she died during "Raised on Robbery". So how long has it been exactly?
- When Dr. Ogden takes the job in Buffalo, why doesn't Murdoch try to get a job there as well? While it was difficult for a woman doctor to find a position, as she pointed out, surely it wouldn't be so hard for a detective of Murdoch's reputation to secure a position in the Buffalo police department. (The obvious explanation is that, in the late 19th century, it was inconceivable for a man to sacrifice his career for a woman's career, even for someone as progressive as Murdoch. Still, the thought didn't even occur to him for six months?)
- Medicine is medicine everywhere. Policing and law are significantly different in different countries, so William might well have had to start his career all over again at an American police department, and may have felt the loss of rank, prestige and income too great for him to remain worthy of a woman like Julia, had he taken such a position.
- Word of God confirms that the Bill Murdoch who appeared in the Republic of Doyle episode "If the Shoe Fits" is the descendant of William Murdoch. Both characters are portrayed by Yannick Bisson. However William and Julia's son, Roland, is their son by adoption, as Julia is unable to have children after a botched abortion in her youth. Therefore, Bill would not be related to William by blood, and it would be impossible to be his Identical Grandson. Could this mean that Julia actually isn't barren (we're dealing with late-19th and early-20th century medicine, after all) and she might yet end up pregnant later in the series? Or worse, that Julia is William's first wife, and Bill is his grandson by another woman?
- Or worse William Murdoch and his fiancee Elizabeth Milner did have a child. On a pretext, Elizabeth could have been sent away to hide the pregnancy. Without Murdoch knowing. Elizabeth could have died due to consumption, and complications due to childbirth.
- On the other hand, for all we know William could have simply outlived Julia by several years, long enough to form a romantic relationship with another woman in his senior years. This wouldn't have to mean Julia died all that young, only that William was willing to court a new wife who was young enough to have children after he'd mourned sufficiently. Sad, but reasonably bittersweet also, if Julia made him promise not to give up on finding happiness again.
- Or Julia's experimentation with fertility treatments in season 11 are successful.
Headscratchers / Murdoch Mysteries