History Main / MasterPoisoner

** A Master Alchemist in ''Morrowind'' and ''Oblivion'' can produce a staggering variety of poisons with StandardStatusEffects beyond all those listed in the trope definition. Though poisons in-game aren't as instantly lethal, a full stack of damage-over-time effects make it a foregone conclusion. Replace one of those with fatigue-drainer, and you can safely look your opponent in the eye as it dies.

* Durzo Blint, of the ''Night Angel Trilogy'' is an assassin who excels at poisoning.

* In TheDemonPrinces, the planet Sarkovy's [[PlanetOfHats Hat]] is brewing and finding creative ways to administer poisons. The higher ranks of their grand masters can be {{Poisonous Person}}s, although in a touch of realism, these people tend to die rapidly themselves. Hero Kirth Gersen spent several instructive years there, to the point of being able to outwit and infect a rival Master Poisoner.

* Locusta in the ''DoctorWho'' serial "[[Recap/DoctorWhoS2E4TheRomans The Romans]]".

* ''{{Command and Conquer}}: Generals'' has the notorious Dr. Thrax, one of the [[TerroristsWithoutACause GLA's]] generals. Under his command, almost all of the units that normally use high explosives instead use a biochemical cocktail called Anthrax Beta/Gamma. [[CrowningMomentOfFunny He got his degree in bacteriology from a mail-order college.]]

* ''Command and Conquer: Generals'' has the notorious Dr. Thrax, one of the [[TerroristsWithoutACause GLA's]] generals. Under his command, almost all of the units that normally use high explosives instead use a biochemical cocktail called Anthrax Beta/Gamma. [[CrowningMomentOfFunny He got his degree in bacteriology from a mail-order college.]]

* The entire Skaven race from ''{{Warhammer}}''.

* Due to his...unusual...hobbies, Earl Cain Hargreaves of Godchild is very knowledgeable in-and collects-poisons.

* Livia, and later Agrippina, from ''IClaudius''.

* Kodachi Kuno from ''RanmaOneHalf''.

* ''DungeonsAndDragons'' [[CareerKillers Assasins]] in all editions that has them as a class or kit.

* In the D&D lawyer friendly spinoff {{Pathfinder}}, a number of classes such as rogues, assassins and the currently experimental ninjas are proficient poisoners, but it's the [[TheRedMage Alchemist]], which can not only make poisons, but becomes completely immune to them, can refine them into a more deadly, harder to resist form, make them last longer on the weapon and make them in a fraction of the time with reduced material costs.

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* Lucrezia Borgia is often portrayed as this; see HistoryMarchesOn for a discussion.
** ''All'' of the Borgias had the reputation of poisoners, not just Lucrezia. It was probably untrue of Lucrezia and Rodrigo ([-AKA-] Pope Alexander VI), but likely enough in Cesare's case.

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* In ''{{Inuyasha}}'' there are several, including Sango, Yakorou Dokusen and Mukotsu from the Band of Seven who almost succeeded [[spoiler: in killing half the titular character's team]].
* Himeko of ''GetBackers'', and also her brother.
* Abe no Kaii in the ''LoneWolfAndCub''.

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* The poisoner from ''[[TheFirstLaw Best Served Cold]]'' by Joe Abercrombie, Morveer.

** Another ''Batman'' villain, The Joker, was a prodigy at this. In both the [[Film/{{Batman}} 1989 movie]] and the [[BatmanTheAnimatedSeries animated series]], he developed "binary compounds" by which he could succeed in murdering victims with the ''second'' exposure, thus appearing not to have been directly responsible for their deaths. The man's chemistry skill is such he can create incredibly toxic compounds out of nothing but the contents of a janitor's closet.

* Abe no Kaii in the LoneWolfAndCub

* One of the Whatchamawhosit Seven, that QuirkyMinibossSquad from ''{{Inuyasha}}''.

* In ''WorldOfWarcraft'', one of the abilities of the Rogue class is concocting and applying poisons (usually to their own weapons). The Assassination talent tree partly focuses on this particular ability.
** While rogues are still totally all about using and applying poisons, they have long since nixed the ability to concoct your own poisons. The reason they stated was that buying tons of ingredients to make your own poisons was an unnecessary and cumbersome extra step, so now rogues buy all their poisons pre-made.