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* ''Webcomic/EnnuiGo'': The SJW with his many buttholes, Noah's freakish elephant penis, and Jerry all come to mind.

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* ''Radio/JourneyIntoSpace'': In ''The Red Planet'' and ''The World in Peril'', the Martians altered the biology of many humans so that they could survive in the Martian atmosphere.
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* In ''Webcomic/AskWhitePearlAndStevenAlmostAnything'', Steven is the HalfHumanHybrid son of Greg Universe and White Diamond. White Diamond [[LargeAndInCharge was taller than the Crystal Gem's temple]] and her gem large enough to match. Because of this, ''Steven lacks a human brain'', the majority of his mother's gem occupying the majority of his skull cavity and the pointed end of her gem visible as a small horn on his head.


* Humans in the MarvelUniverse are very different from RealLife humans thanks to the Celestials' experiments on their ancestors. All humans possess the potential to manifest superpowers if the right conditions are met. Different subspecies have different triggers:
** Eternals and Deviants are born with their powers: Eternals get immortality and the ability to manipulate cosmic energy (at the cost of constantly needing to vent off heat), and the Deviants get BodyHorror.
** Comicbook/TheInhumans were further messed up by Kree experiments, and now manifest random powers and mutations through exposure to Terrigen Mist in a process called terrigenesis. People descended from Inhumans who mated with baseline humans also have a chance of undergoing terrigenesis or dying.
** Mutants usually manifest their mutations at puberty, though a rare few manifest their mutations at birth. This is apparently due to an extra gene dubbed the X-gene. Certain outside conditions seem to be able to cause the X-gene to manifest more often in the human population -- the detonation of the atomic bombs during World War II triggered a rise in mutant birthrates. It's also implied that every mutant is actually a RealityWarper who unconsciously alters reality in a different way.
** Baseline humans usually never manifest powers on their own, but exposure to certain (usually life-threatening) conditions can cause them to appear.



* ''Franchise/StarWars'': Humans, as well as all other living species in TheVerse, possess "midi-chlorians", mysterious organelles which have some intricate connection to the Force.
** [[FanWank It's a bit more complicated than that.]] The [[Franchise/StarWarsLegends old expanded universe]] has gone back and forth over what the role of Midi Chlorians actually are, though [[Franchise/StarWarsExpandedUniverse the new Expanded Universe]]'s current stance is that midi-chlorians act as a go-between for the [[LifeEnergy Living Force]] and the [[SentientCosmicForce Cosmic Force]].



* Humans from ''VideoGame/DarkSouls'' are a race of beings descended from the Furtive Pygmy, who created mankind by sharing fragments of the Dark Soul. Because of this, mankind has an inherent link to the dark, with "Humanity" implied to be fragments of the dark soul watered down over the years and maintaining mankind's human characteristics. When the first flame starts to fade, mankind becomes marked with the darksign, a curse that leaks Humanity out of humans [[spoiler:cursed onto mankind when Gwyn branded the pygmys with fire in hopes of controlling the Dark]] and turning them into the Undead, unable to die and slowly wasting away until they become Hollows. An alternative title for "the Age of Dark" is even called "the Age of Man."



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* Humanity in ''Franchise/Ben10'' might seem weak compared to some other species in the series, but they have some unique qualities to them. One is that they're one of the few species who are [[WitchSpecies able to use mana and magic]], although a few others are capable of it as well. Their other, more unique trait is that they can interbreed with any other intelligent species. ''Any.'' This includes things like Pyronites, who are literally lava people who live on a freaking sun. Nobody knows how or why they're capable of this, but a good chunk of humanity has at least some alien ancestry.
** However, it turned out that [[spoiler:the supposed child of a human and a Pyronite encountered in the show was actually a full human who had some experiments done on him to infuse him with Pyronite DNA, then given FakeMemories of his parentage to cover up the existence of the group who experimented on him. So while a human and Pyronite offspring may be possible in theory, it probably isn't in practice]].
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* Even ignoring people with Devil Fruit powers, and those who are just {{Gonk}}s, apparently humans in the world of ''Manga/{{One Piece}}'' can grow to gigantic size (case in point: Blackbeard is 11 feet tall. Gecko Moriah, the tallest non-giant character, is around 22 feet). It may not be that common, but nobody seems to think it's worthy of comment, either. We also see explicitly human characters who have simian facial features and even ''grow horns'', apparently totally naturally. And various other "nonhuman" races like Giants and Fishmen are referred to as "tribes" and can interbreed with humans, implying [[HumanSubspecies they're very closely related]]. And apparently willpower and just general power have an effect on biology too; Ace's mom held her pregnancy in for ''years'' through sheer willpower to protect him from people seeking to end his bloodline, and [[spoiler:one of the post-timeskip Admirals]] states he hasn't eaten in ''three years'' because it's too big a hassle, but he's apparently no worse for the wear.

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Compare and contrast to OurHumansAreDifferent, which is about ''all'' humans being significantly different than in real life.

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* The titular ''Anime/{{Canaan}}'' has synesthesia, which translates as AuraVision for her. One example has her seeing the bits of code needed to hack a door that a professional hacker couldn't get. [[spoiler: Too bad that hacker was [[BigBad Alphard]]]]


* The title character from ''Anime/SkullFaceBooksellerHondaSan'' can do the typical anime SweatDrop and BloodFromTheMouth, despite ''being a skeleton.''

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* The title character from ''Anime/SkullFaceBooksellerHondaSan'' ''Manga/SkullFaceBooksellerHondaSan'' can do the typical anime SweatDrop and BloodFromTheMouth, despite ''being a skeleton.''

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* In Creator/GregEgan's novel ''Distress'', one CrazySurvivalist has loaded himself up with so much BioAugmentation to survive any possible apocalyptic scenario that he doesn't even have DNA in his cells anymore. He can also digest tire rubber in a pinch.


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* ''Webcomic/AliceGrove'': Referenced in a conversation between Gavia (a {{Nanobot|s}}-enhanced cyborg) and Sedna (a SuperSoldier with ''extensive'' modifications, including [[spoiler:quantum entanglement with a black hole to let her violate the laws of thermodynamics]]):
--> '''Gavia:''' ''[Changes her skin colour with a thought]'' I [[spoiler:[[DePower lost my nanotech]]]]. I'm not ''baseline''.\\
'''Sedna:''' Hey, preachin' to the choir, here. I can ''photosynthesize'' if I have to.


* Even ignoring people with Devil Fruit powers, and those who are just {{Gonk}}s, apparently humans in the world of ''Manga/{{One Piece}}'' can grow to gigantic size (case in point: Blackbeard is 11 feet tall. Gecko Moriah, the tallest non-giant character, is around 22 feet). It may not be that common, but nobody seems to think it's worthy of comment, either. We also see explicitly human characters who have simian facial features and even ''grow horns'', apparently totally naturally. And various other "nonhuman" races like Giants and Fishmen are referred to as "tribes" and can interbreed with humans, implying they're very closely related. And apparently willpower and just general power have an effect on biology too; Ace's mom held her pregnancy in for ''years'' through sheer willpower to protect him from people seeking to end his bloodline, and [[spoiler:one of the post-timeskip Admirals]] states he hasn't eaten in ''three years'' because it's too big a hassle, but he's apparently no worse for the wear.

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* Even ignoring people with Devil Fruit powers, and those who are just {{Gonk}}s, apparently humans in the world of ''Manga/{{One Piece}}'' can grow to gigantic size (case in point: Blackbeard is 11 feet tall. Gecko Moriah, the tallest non-giant character, is around 22 feet). It may not be that common, but nobody seems to think it's worthy of comment, either. We also see explicitly human characters who have simian facial features and even ''grow horns'', apparently totally naturally. And various other "nonhuman" races like Giants and Fishmen are referred to as "tribes" and can interbreed with humans, implying [[HumanSubspecies they're very closely related.related]]. And apparently willpower and just general power have an effect on biology too; Ace's mom held her pregnancy in for ''years'' through sheer willpower to protect him from people seeking to end his bloodline, and [[spoiler:one of the post-timeskip Admirals]] states he hasn't eaten in ''three years'' because it's too big a hassle, but he's apparently no worse for the wear.

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* The title character from ''Anime/SkullFaceBooksellerHondaSan'' can do the typical anime SweatDrop and BloodFromTheMouth, despite ''being a skeleton.''


* Even ignoring people with Devil Fruit powers, and those who are just {{Gonk}}s, apparently humans in the world of ''Manga/{{One Piece}}'' can grow to gigantic size (case in point: Blackbeard is 11 feet tall. Gecko Moriah, the tallest non-giant character, is around 22 feet). It may not be that common, but nobody seems to think it's worthy of comment, either. We also see explicitly human characters who have simian facial features and even ''grow horns'', apparently totally naturally. And various other "nonhuman" races like Giants and Fishmen are referred to as "tribes" and can interbreed with humans, implying they're very closely related.

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* Even ignoring people with Devil Fruit powers, and those who are just {{Gonk}}s, apparently humans in the world of ''Manga/{{One Piece}}'' can grow to gigantic size (case in point: Blackbeard is 11 feet tall. Gecko Moriah, the tallest non-giant character, is around 22 feet). It may not be that common, but nobody seems to think it's worthy of comment, either. We also see explicitly human characters who have simian facial features and even ''grow horns'', apparently totally naturally. And various other "nonhuman" races like Giants and Fishmen are referred to as "tribes" and can interbreed with humans, implying they're very closely related. And apparently willpower and just general power have an effect on biology too; Ace's mom held her pregnancy in for ''years'' through sheer willpower to protect him from people seeking to end his bloodline, and [[spoiler:one of the post-timeskip Admirals]] states he hasn't eaten in ''three years'' because it's too big a hassle, but he's apparently no worse for the wear.


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* ''Franchise/StarWars'': Humans, as well as all other living species in TheVerse, possess "midi-chlorians," mysterious organelles which have some intricate connection to the Force.
** [[FanWank It's a bit more complicated than that.]] The [[Franchise/StarWarsLegends old expanded universe]] has gone back and forth over what the role of Midi Chlorians actually are, though the [[Franchise/StarWarsExpandedUniverse the new Expanded Universe]]'s current stance is that midi-chlorians act as a go-between for the [[LifeEnergy Living Force]] and the [[SentientCosmicForce Cosmic Force]].

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* ''Franchise/StarWars'': Humans, as well as all other living species in TheVerse, possess "midi-chlorians," mysterious organelles which have some intricate connection to the Force.
** [[FanWank It's a bit more complicated than that.]] The [[Franchise/StarWarsLegends old expanded universe]] has gone back and forth over what the role of Midi Chlorians actually are, though the [[Franchise/StarWarsExpandedUniverse the new Expanded Universe]]'s current stance is that midi-chlorians act as a go-between for the [[LifeEnergy Living Force]] and the [[SentientCosmicForce Cosmic Force]].
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* ''Franchise/StarWars'': Humans, as well as all other living species in TheVerse, possess "midi-chlorians", mysterious organelles which have some intricate connection to the Force.
** [[FanWank It's a bit more complicated than that.]] The [[Franchise/StarWarsLegends old expanded universe]] has gone back and forth over what the role of Midi Chlorians actually are, though [[Franchise/StarWarsExpandedUniverse the new Expanded Universe]]'s current stance is that midi-chlorians act as a go-between for the [[LifeEnergy Living Force]] and the [[SentientCosmicForce Cosmic Force]].



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* ''Series/DoctorWho'': The Doctor's companions, as a result of exposure to the Time Vortex, are altered on a genetic level. Results include altered white blood cells and RippleEffectProofMemory.



* In ''Series/{{Supernatural}}'' the [[Characters/SupernaturalSpecialChildren Special Children]] develop psychic powers, the ability to kill with a touch, and super strength, after being fed demon blood as infants.




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* In ''Series/{{Supernatural}}'' the [[Characters/SupernaturalSpecialChildren Special Children]] develop psychic powers, the ability to kill with a touch, and super strength, after being fed demon blood as infants.



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* In ''Webcomic/QuantumVibe'' when Seamus is originally introduced he has some physiological abnormalities due to a botched [[LongevityTreatment rejuvenation]], gigantism combined with a metabolic disorder that made him morbidly obese, nerves in his hair, and the ability to fart at will. He had most of the problems fixed during the Luna arc, though he's still pretty tall.

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* In ''Webcomic/QuantumVibe'' when Seamus is originally introduced he has some physiological abnormalities due to a botched [[LongevityTreatment rejuvenation]], gigantism combined with a metabolic disorder that made him morbidly obese, nerves in his hair, and the ability to fart at will. He had most of the problems fixed during the Luna arc, though he's still pretty tall.
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* In ''Webcomic/QuantumVibe'' when Seamus is originally introduced he has some physiological abnormalities due to a botched [[LongevityTreatment rejuvenation]], gigantism combined with a metabolic disorder that made him morbidly obese, nerves in his hair, and the ability to fart at will. He had most of the problems fixed during the Luna arc, though he's still pretty tall.



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*** Anything can become this when you think about it the right way. The mouth for example? It's a hole in your skull lined with exposed bone (teeth), housing a exposed muscle that is detached at one end (tongue) that people touch with their exposed muscle for pleasure (kissing), and used to put various things inside you (food). Common examples are the heated-with-fire muscles of animals (cooked meat), flower heads (broccoli), the ejected and empty "womb" of a bird (eggs), and bug puke (honey).

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*** ** Anything can become this when you think about it the right way. The mouth for example? It's a hole in your skull lined with exposed bone (teeth), housing a exposed muscle that is detached at one end (tongue) that people touch with their exposed muscle for pleasure (kissing), and used to put various things inside you (food). Common examples are the heated-with-fire muscles of animals (cooked meat), flower heads (broccoli), the ejected and empty "womb" of a bird (eggs), and bug puke (honey).



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* Speaking of MisterSeahorse, there is the... ''concept'' of Omegaverse. More details can be found on that page, but the least {{Squick}}y explanation is this trope applied to BizarreAlienSexes.

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