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* Edward Elric of FullmetalAlchemist lost his right arm and his brother lost his entire body performing forbidden alchemy, which put him on a self-imposed RedemptionQuest to restore his brother's real body. At the end of the story, [[spoiler: he has his right arm and his brother back, but Edward had to give up his ability to perform alchemy.]]

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[[folder: WesternAnimation]]
* In one "Treehouse of Horror" episode of ''TheSimpsons'', left-handed Bart turns out to be the evil twin of Hugo Simpson. Bart's left-handedness is never brought up in the episode though.


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[[folder: WesternAnimation]]
* In one "Treehouse of Horror" episode of ''TheSimpsons'', left-handed Bart turns out to be the evil twin of Hugo Simpson. Bart's left-handedness is never brought up in the episode though.

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[[folder: WesternAnimation]]
* In one "Treehouse of Horror" episode of ''TheSimpsons'', left-handed Bart turns out to be the evil twin of Hugo Simpson. Bart's left-handedness is never brought up in the episode though.
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* Not quite sure if it counts, but Bowser bats and pitches left-handed in Mario Super Sluggers.
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* Notably inverted with a lot of the characters Shigeru Miyamoto creates. [[SuperMario Mario]] and [[TheLegendOfZelda Link]] are both left-handed, and Miyamoto himself is ambidextrous, preferring his left hand.
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Additionally, in older times, left-handedness was often a sign of evil or trickery because of the fact that people would shake hands with their right in order to show that they were friendly and [[NothingUpMySleeve didn't have weapons]]. A lefty could shake with their right hand, grasping the other person's dominant hand, and attack with their weapon in their left hand while the other was defenseless.

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Additionally, in older times, left-handedness was often a sign of evil or trickery because of the fact that people would shake hands with their right right, grabbing each other by the wrists, in order to show that they were friendly and [[NothingUpMySleeve didn't have weapons]]. A lefty could shake with their right hand, grasping the other person's dominant hand, and attack with their weapon in their left hand while the other was defenseless.
defenseless. Also, during the Middle Ages, towers were built so defenders would have no problem swinging their swords down staircases while attackers would have loads of problems swinging up. However, this only applied if both were right handed; if the attacker were left-handed, the two would be evenly matched.
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* Inverted by {{Nanoha}}, who is a left-handed hero in a series full of right-handed villains. Unless, of course, you take her {{fanon}} [[BloodKnight reputation]] into consideration...

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* Inverted by {{Nanoha}}, who is a Nanoha, the left-handed hero in a series heroine of the ''LyricalNanoha'' series, which full of right-handed villains. Unless, of course, you take her {{fanon}} [[BloodKnight reputation]] into consideration...
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* The lead characters of ''Parasyte'' are a young man named Shinichi and the alien parasite that has possessed/replaced his right hand. Their relationship is one of the main foci of the series, especially re: Shinichi losing part of his humanity. As early as the first volume, the LoveInterest intuits there's something weird about his right hand and switches around him to hold his left instead.

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* The lead characters of ''Parasyte'' ''{{Parasyte}}'' are a young man named Shinichi and the alien parasite that has possessed/replaced his right hand. Their relationship is one of the main foci of the series, especially re: Shinichi losing part of his humanity. As early as the first volume, the LoveInterest intuits there's something weird about his right hand and switches around him to hold his left instead.
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** [[DontExplainTheJoke "Dexter" is also derived from the latin word for the right, or right hand, making the character name an obvious contradiction.]]

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* The two models of the [[PokemonColosseum portable Snag Machine]] are depicted as being worn on the left arm. Neither of their wielders are particularly nasty ([[AntiHero though one moreso than the other]]), but the folks behind inventing the device are [[CompleteMonster the epitome of evil]] in the Pokeverse.
** As a comparison, in ''XD'', Michael always makes a regular catch (at the Poke Spots, given that's where wild Pokemon appear from time to time) or calls out a Pokemon with his right hand. He only uses his left when he needs to make a Snag.
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* The official art for ''Castlevania: Symphony of the Night'' depicts [[spoiler:cursed-by-Dracula]] Richter Belmont as a lefty; he is right-handed in the prior depictions of him. Hint hint much.
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* An odd example occurs in the online game ''ImprobableIsland'', where one of the monsters you can encounter is called "Sinister Dexter", an AffectionateParody of, well, {{Dexter}}. His moves are all based on being left-handed. [[RealityIsOutToLunch It's that kind of game]].
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* Gin from ''DetectiveConan'' is left-handed.

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* Gin from ''DetectiveConan'' is left-handed. Also, there is a case Conan solves by realizing a man had been replaced by a duplicate because the fake was left handed and the original was not.
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*** You're not alone: a reader of the Nitpicker Guide apparently did a half-blind experiment where he threw a ball at people and found regardless of which hand they were dominant in, they caught the ball with the most convenient hand (it depended on which angle it was being caught from).
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Not related to [[StrawmanPolitical the political left]] (YourMileageMayVary as to if they are evil).
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[[folder: Film]]
* [[TheFaceless Keyser Soze]] in ''TheUsualSuspects'' is left handed. A clue to his identity occurs early in the movie, when [[spoiler:Verbal Kint tries to light a cigarette by holding the lighter in his right hand and opening it with his [[ObfuscatingDisability cerebral palsy-afflicted left hand]], but can't do it]].

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No page image present


* As shown by his page image, GreenLantern villain {{Sinestro}} wears his [[GreenLanternRing power ring]] on his left hand.

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* As shown by his page image, GreenLantern villain {{Sinestro}} wears his [[GreenLanternRing power ring]] on his left hand.
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** Kain Highwind, a party member from ''FinalFantasyIV'', is left handed, which is shown by having weapon and shield slots in his inventory screen reversed. No points for guessing what he does, especially with [[NameOfCain a name]] [[CainAndAbel like that]]. Though he does get better... [[HeelFaceRevolvingDoor somewhat]].

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*The lead characters of ''Parasyte'' are a young man named Shinichi and the alien parasite that has possessed/replaced his right hand. Their relationship is one of the main foci of the series, especially re: Shinichi losing part of his humanity. As early as the first volume, the LoveInterest intuits there's something weird about his right hand and switches around him to hold his left instead.
**The original English translation was flipped and 'Migi' was named 'Lefty' instead.
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Added C&A, Narbonic

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[[folder: Webcomics]]

* ''Casey and Andy'': Satan is left-handed.
* ''Narbonic'': Caliban is left-handed.

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** As does Alan Scott (the Golden Age GL), inverting this trope.
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...spoiled why? He\'s an obvious bad guy from the start


* In ''TheWorldEndsWithYou'' [[spoiler: Sho Minamimoto]] has a black left hand.

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* In ''TheWorldEndsWithYou'' [[spoiler: Sho Minamimoto]] Minamimoto has a black left hand.
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[[folder: Comic Books]]
* As shown by his page image, GreenLantern villain {{Sinestro}} wears his [[GreenLanternRing power ring]] on his left hand.
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* Played for laughs in some comedy (?) show called ''Inside Scoop'': [[http://www.youtube.com/watch?v=1GEI7HKE_D4 Ban Left Marriage!]]
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[[folder: Tabletop Games]]
* ''{{Paranoia}}'': "Left-handedness is one of the ten early warning signs of Commie mutant treason!"
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* In ''SuperSmashBros'', Master Hand is a giant, floating, apparently benign right hand who created the world that the characters find themselves in, and lives to be the ultimate challenge for heroes. His EvilTwin is the Crazy Hand, the left hand of the pair, who laughs maniacally upon his entrance and whose attacks and general movements are both bizarre and incredibly erratic. Whereas Master Hand is said to be a benign force and to represent the creative nature of a child, Crazy Hand is a destroyer, and supposedly represents that same child's more sadistic qualities.
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**That one actually bothered me, even in the Sherlock Holmes story alluded to in this episode. Think of baseball players. They are (like most of the population) right handed. Their mitts are, therefor, on their left hands so as to allow them to keep their dominant hands free of obstruction.
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* The main villain of ''FinalFantasyIV'', Golbez, is left-handed. However, you only learn this when [[spoiler:he's freed from brainwashing (done by the ''real'' villain) and becomes a protagonist in the sequel]]. He wields weapons in his left and shields in his right.

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* The main villain of ''FinalFantasyIV'', Golbez, is left-handed. However, you only learn this when [[spoiler:he's freed from brainwashing (done by the ''real'' villain) and becomes a protagonist in the sequel]]. He wields weapons in his left and shields in his right.
right. Similarly, [[spoiler:Kain]] is left-handed, and ends up brainwashed to fight for the villain.

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