These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Badass Decay: Some feel that Minerva being turned human has done this to her, as well as made her less unique. Doubly so as she actually turns smaller (less than a head taller than Heather) and less strong and muscular in human form.
Die for Our Ship: Darien was given this treatment by Spinnerette/Mecha-Maid shippers before Heather and Mecha Maid hooked up.
Fan Dumb: Many fans are a little too quick to write off anyone who critiques the comic in any way as a "troll" who "doesn't get" the comic, and some will even resort to the claim that anything someone has an issue with was SO OBVIOUSLY planned from the very beginning and heavily foreshadowed.
In Heather's little news clipping shrine to her superheroing, more than half of the clippings and photos shown are of her and MM in close physical contact. Sahira even uses one of them (of MM openly checking out Heather's ass) to help drive home the suggestion that Mecha Maid is a lesbian. This is Hypocritical Humor as well, since Sahira really seems to like touching Heather. Including in that very comic.
Sahira has outright stated she thinks that Mecha Maid wants to be more than just friends with Heather. Confirmed at the end of Chapter 6 — Mecha Maid admits she finds Heather attractive, but denies having any romantic attraction to her. Her thought bubble at the end says otherwise. Heather is too clueless to realize the subtext.
It's just fanart... but here you go.◊(slightly NSFW)
Katt O'Nine Tails can add this to her repertoire. There's also Mecha Maid's reaction when she walks in on the following tail-massage. She can mistake it for a) Katt attacking Spinnerette. b) The two of them getting it on and so being jelous or c) both. In any case on a second readthrough (or just to anyone with Yuri goggles enabled) it can be interprated very much as a "lay of my crush!" reaction.
Evil Spinerette/Alexis kissed a girl that was taunting her and made up some fake story about how a Drider's kiss creates a magical bond of romance. One week later, the girl practically throws herself at Alexis. Alexis admitted to Heather that she was probably a closet lesbian her entire life and now has an excuse to come out. It was all part of Evil Spinnerette's cunning plan to fool Heather into helping her with her latest drider-creation ritual.
Meaningful Name: Alexis Woodrow's first name might be a Shout Out to famous Rich Bitch Alexis Carrington (Joan Collins) of Dynasty, as this Alexis, like the original, comes from a wealthy family. Also of note is that "Drow" is in her name, Drows being the elven race from Dungeons and Dragons that Driders had once been.
Memetic Mutation: When Katt throws a car at Dr Universe, take a look at the car's license plate.
The strip that shows why Tiger decided to pursue superheroing is either really sad or too melodramatic. Hey, "Vary" is the key word here.
After Mecha Maid gets electrocuted and can't breathe, she tells Heather to take her to the "superhero hospital". It's a serious moment, but the way it was worded just made it seem silly.
When Marilyn lets out her Anguished Declaration of Love for Heather, it's meant to be a huge Drama Bomb...but the sight of Heather's nipples poking through her suit can kind of deflate it.
Villain Sue: Evil Spinnerette had shades of this in Chapter 7. She not only figured out Heather's secret identity, but she also fooled Spinnerette into helping her and then effortlessly trounced her in battle. The whole chapter almost reads like a fanfic by someone zealously devoted to the character.