Tropes covered by the short and the series:
- Bug War: Mostly one-sided. Characters try to dispose of Itsy for being a spider and he's just defending himself.
- Cats Are Mean: Cat/George
- David Versus Goliath
- Determinator: The Exterminator
- Dumb Muscle: The Exterminator
- Eccentric Exterminator
- Hey, It's That Voice!: Frank Welker as Itsy, Matt Frewer as the Exterminator in the series, Jim Carrey as the Exterminator in the short, Thora Birch as Little Girl/Leslie in the short.
- Kill It with Fire: One of the Exterminator's tools is a flamethrower.
- Meganekko: Little Girl/Leslie
- Stern Teacher: Music Teacher/Adrianne
- Top-Heavy Guy: The Exterminator
Tropes exclusive to the short:
- The Ahnold: The Exterminator after the Robotic Reveal.
- More Dakka: Turned Up to Eleven
- No Name Given
- Techno Babble:Music Teacher: What is that?The Exterminator: It's a high-tech microchip thermonuclear light-sensitive radioactive blue-screen laptop computer generator triple decker arachnid detector and Etch-a-Sketch. Any more questions?
Tropes exclusive to the series:
- Lawyer-Friendly Cameo: In one episode the Exterminator kills Expies of Bambi and his mother.
- Negative Continuity: For one thing, the Exterminator is no longer a robot.
- The Other Darrin: Frank Welker was the only one to return for the series.
- Panty Shot: Leslie in a couple of episodes, especially "State Fair Itsy."