A comic about an old house, a geek, a cute transvestite, a tall lesbian, and several ghosts - with guardian angels, personal demons and not-so-alien aliens featuring in later storylines. Found here Occasionally NSFW.Tropes Used
Alien Abduction: Twice so far to Ace - the first time he woke up and caused havoc, the second time he was recruited specifically because he caused havoc...
Fate Worse than Death: Lady Si was threatened with this: "One is embedded alive in a giant diamond the size of a large coffin, like a fly in amber, and put on display. It's not fatal to an Eternal. As long as there's sufficient ambient energy, the nano-machines keep us alive and aware."
Forgotten First Meeting: The latest addition to Ace's Unwanted Harem is a very tall Ainu girl who ran away from home because she was always being mocked for her size, determined to find the only boy who'd ever called her pretty - a young Gaijin boy she'd found lost back in Hokkaido, and helped to find a police-box. Cue the revelation that Ace had gotten lost during a trip to Hokkaido with his mom when he was a kid, and had been helped by a pretty redhead...
Green-Skinned Space Babe: Child!Ace and Teen!Ace meet several Orion females (conveniently, males aren't trusted to be let loose on deck) - although their green skin is due to ingesting pills which replace melanin with chlorophyll.
Human Outside, Alien Inside: Inverted. Orions look alien, with their green skin and antenna, but are human (separated from Terra for a few thousand years) and the antennae are cybernetic, connected to a neural implant.
Incompatible Orientation: Rocky and Carly used to date. It's implied that this is the reason it didn't work out. Luna still hasn't given up on Carly either, despite the fact that he's a gay transvestite. Rocky and Carly eventually resume their relationship.
Jacob Marley Apparel: Ghosts appear in what they died in. Souls however (there's a difference here) appear naked.
Unsettling Gender-Reveal: Even though there was no romantic involvement, this happens when Ace finds out that Carly is actually Carl Lee.
Unwanted Harem: Ace's is made up of an heiress supermodel, her best friend, a psychic nurse/stripper, a policewoman, a ghost who later becomes an angel, that ghost's great-granddaughter, and his pregnant ex-girlfriend from high school. Lampshaded by Carly here.
...and a very tall redheaded japanese girl tied to him with a Red String of Fate worthy of the cheesiest of romantic anime.
In the Teen!Ace in Space arc, several aliens and even a maintenance droid (!)