Uncle Leo appears on this show a few times as well.
Chris Elliot as Amy's brother
Fred Willard as Amy's father
The Other Darrin: Amy's brother was initially played by Paul Reubens. When the character returned, he had a different name and actor, but was clearly meant to be the same comic book store owner that grew attached to Ray. Off screen, Reubens was arrested on child pornography charges, and although he managed to stay out of jail, Ray Romano didn't like the idea of bringing him back and requested that the character be recast. Oddly, not only was the character recast, but renamed (Russell to Peter)
Nemo was originally played by Joseph V. Perry, but the actor died in February 2000; his character was subsequently played by Robert Ruth in "What Good Are You?" and "Stefania Arrives".
Post Script Season: The series was originally intended to be only eight seasons long, but Ray Romano and Phil Rosenthal decided to give one last season to the fans. As a result, the final season was a bit shorter than the previous ones.