A swift kick to the groin works on everything, from robots to ghosts to C'thulhu himself.
Zig Zagged: A Shadow Discretion Shot looks like Alice hit Bob in his crotch, but she really kicked him in his thigh. Until Bob is seen with an icepack on his crotch, which he explains he needs to use after falling on a plank of wood, so Alice really did kick Bob in his thigh.
Averted: The two fight, but Alice does not target Bob's groin.
Enforced: "Hits to the manhood are always funny; why don't we include one here?"
All his friends think it was in good humor at the time, but Bob does not survive the groin attack.
Bob survives, but permanent damage is done. A full description of the damage would be... Distasteful at best, but in short, he'll never be a father, and he spends the next week and a half having to call a nurse if he needs to pee.