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The Blood series by Tanya Huff is a set of five books (and plenty of short stories) that was eventually adapted into the television show Blood Ties. It takes place in Toronto, except for the last book being in Vancouver. The heroine is Defective Detective Vicki Nelson, whose retinitis pigmentosa forced her to quit being a cop and become an Occult Detective. Her off-and-on boyfriend/ex-partner Mike Celluci is not terribly thrilled with her choice of lifestyle. Then Vicki ends up meeting Friendly Neighborhood Vampire Henry Fitzroy and partners with/dates/donates blood to him on a regular basis. The fourth main character is Tony Foster, a homeless kid that Vicki recruits to help give Henry blood, and ends up involved with Henry as well. The books in the series are:
Blood Bank, a collection of stories featuring the main characters. There are a few flashback stories involving Henry, but most take place after the final book in the series.
Gods Need Prayer Badly: In Blood Lines, the belief of the immortal sorcerer-priest Tawfik has kept his personal god, Akhekh, alive for a very long time. Unfortunately for him, once the protagonists find out about Akhekh, their belief works just as well, and when Akhekh decides Tawfik isn't performing to expectations it lets him die.
The House Of Tudor: Henry Fitzroy is originally Henry, Duke of Richmond and Somerset, Henry VIII's bastard son.
Hypocrite: Henry is still on the Catholic side of the Reformation centuries later and expresses disapproval of his father's schism and divorces. However, Henry himself is bisexual, and a vampire. Neither of which would endear him to the Catholic Church were he an active parishioner, either in the present or especially back during the 16th Century.
Mad Scientist: In Blood Pact. Henry lampshades this somewhat in pointing out that so long as they conceal his involvement, there is no reason why they cannot simply call the police and have the perpetrators arrested since they are not supernatural in any way and have broken the law. Mike, who normally tries to disagree with Henry as much as possible, cannot argue the point. But Vicki wants revenge...
Magic Pants: Averted. Werewolves cannot change while clothed, so they often go naked on their own property. This leads the neighbors into suspecting that they are...nudists.
Nothing Is The Same Any More: Blood Pact has a whopper of an ending: Vicki receives a death wound, and Mike talks Henry into giving her an Emergency Transformation. Henry does this knowing that it will be the end of his relationship with Vicki. He and Tony then take her off to Vancouver to spend a year learning how to be a vampire, while Mike becomes The Alcoholic. At the end of the book, Vicki returns to Mike all new and different. The fifth book in the series deals with Vicki's relationship to Henry changing now that they are both vampires and in the same territory. Henry is convinced that instinct trumps friendship, Vicki isn't. They end up having to learn to deal with each other in a new way.
Occult Detective: Vicki finds herself becoming this after getting involved with Henry, although she may herself be a Weirdness Magnet, as at least in Blood Pact the weirdness has nothing to do with Henry, and is not actually supernatural either.
Our Vampires Are Different: the usual garlic/cross stuff doesn't affect Catholic Henry. Also, Henry thinks that vampires can't really hang around other vampires without having territorial issues, although Vicki seems to prove it's not as absolute a rule as he thought.
Polyamory: Vicki dates both Mike and Henry with their knowledge (if not exactly ungrudging support, since the two men don't get along very well) until circumstances/moving adjust the situation. Henry dates both Vicki and Tony, with a lot less angst between the parties involved there.
Protectorate: Henry's attitude towards whatever city he's living in. But then again, he got brought up with noblesse oblige.
Really 700 Years Old: Henry, natch. Lampshaded when a jealous Mike, not yet in on the secret, snarks about how much younger than Vicki he is, and can't understand why she's laughing so hard.
Rich Idiot with No Day Job: Henry actually has a night job that he makes money from (see below), but he seems to have saved up well over the years. Plus, well, the crime-fighting with Vicki.
Romance Novel: Henry writes them under the Pen Name "Elizabeth Fitzroy." Mike makes fun of him for this constantly.
Vicki: Elizabeth Fitzroy?
Henry: Why not Elizabeth Fitzroy? She certainly had as much right to the name as I do. note "Fitzroy" is the name given to a king's bastard; Henry is snarking about Queen Elizabeth being born to the second wife of their shared father.
Stealth Pun: Blood Trail is about a pack of werewolves living near London, Ontario...without a single mention of the Warren Zevon song "Werewolves of London."
Undead Tax Exemption: Henry, to a degree. He pays taxes and has all the ID the average civilian would think to look for - but to a police officer doing a thorough examination (Mike, in a fit of very poorly concealed jealousy that's pointed out by...everyone, really) there are enough holes to "drive a Mack truck through". Mike suspects Henry of being in the Mafia, as a result. He's very surprised, when he confronts Vicki with this and she laughs at him when he says it.
Weirdness Magnet: Henry, since he's a vampire, gets this. It may be communicable, or it may be that he attracts others who are like this as well, since both Vicki and Tony prove to be Weirdness Magnets even when Henry is not involved.