Marge: Uh-huh. In what way?
Townsperson: Oh, just in a general kinda way.
- Airheads - Rex
- Armageddon - Rockhound
- Big Fish: Norther Winslow
- The Big Lebowski - Theodore Donald "Donny" Kerabatsos
- Boardwalk Empire - Enoch "Nucky" Thompson
- Con Air - Garland "The Marietta Mangler" Greene
- Desperado - Buscemi
- Fargo - Carl "The Guy Who Got Fed Into The Woodchipper" Showalter
- Final Fantasy The Spirits Within - Neil Fleming
- Ghost World - Seymour
- The Grey Zone - 'Hesch' Abramowics
- Living in Oblivion
- Monsters, Inc. - Randall Boggs (voice)
- Monsters University - Randall Boggs (voice)
- Hotel Transylvania - Wayne
- Reservoir Dogs - Mr. Pink
- The Sopranos - Tony "Tony B" Blundetto/ Man
- Tales from the Darkside: The Movie - Bellingham
- Things to Do in Denver When You're Dead - Mr. Shhh
- Chronically Killed Actor: Especially in The Coen Brothers movies, and the brothers note that his remains get smaller and smaller through each film.
- It Is Pronounced Tro-PAY: His last name is pronounced "Boo-seh-mi," not "Boo-she-mi," as many people seem to think. He finds the mispronunciation annoying. The latter pronunciation is nonetheless technically correct, as Buscemi has commented "I had to go to Sicily to find out I pronounce my name wrong".
- Jerkass: Most of the characters he plays.
- Jerkass Woobie: Invoked; many of his characters would be sympathetic if they weren't so unpleasant or ruthless.
- Lean and Mean: He's quite cadaverous.
- Lunatic Loophole : Armageddon, Con Air, Reservoir Dogs.
- Money, Dear Boy: If a job pays well enough, he'll generally do it.
- Mean Character Nice Actor: Despite playing immoral/amoral weasels, he has been described as a consummate professional whom everyone likes. A former fire-fighter, he immediately went to his old firehouse and helped look for survivors of the 9/11 attacks.
- Older Than They Look: He's in his 50s now, but still looks like he's in his 40s. In Airheads, he was 36 when he played the 20-something metalhead Rex, and was more convincing than actual (then-)20-something costars Brendan Fraser and Adam Sandler.
- Playing Against Type:
- Boardwalk Empire, as noted above. Enoch Thompson is a powerful, charming Don, leading a successful career as a charismatic politician and powerbroker, a commanding gangster, and all-around king of Atlantic City.
- Donny in The Big Lebowski, a nice, upbeat, naive guy who's never allowed to speak for more than a second. The last part was done as a nod to the fact the his character in Fargo wouldn't shut up.
- An earlier example is In The Soup in which his character is a struggling but Sweet Film Director with an unrequited crush on Jennifer Beals' character
- His character in the Tales from the Crypt episode "Forever Ambergris" is a nice (if naive) fellow. Among other things, he's, a gifted photographer who either doesn't notice how gifted he is or just doesn't let it go to his head.
- In the German biopic John Rabe, he plays a heroic American doctor.
- Small Name, Big Ego: Many of his characters, but Fargo's Carl Showalter stands out. Armageddon finally let him play a character who really was as smart as he thought he was. Best shown in an episode of Homicide Life On The Street where his character is a pretentious longshoreman with delusions of genius who talks down to the detectives whom he views as inferior. They bring in his copy of a Latin manuscript which he cannot read but which Pembleton can.
- What Could Have Been: