Alien vs. Predator: Machiko Noguchi. The only human (much less female) to not only be accepted into the ranks of the Predators, but also thrive among them as a peer.
Astro City: Being set in a world of superheroes, many of the female supers fall into this trope.
A notable subversion is Martha "Sully" Sullivan, who uses her telekinetic powers to do special effects for movies and television. Sully may not be a hero or a villain, but she's shown that she can kick someone's ass if she needs to. It helps that whenever some idiot supervillain doesn't get the hint that Sully and the rest of the Sideliners aren't interested in whatever they're offering, said villain grossly underestimates just what they are capable of.
Body Bags: Panda Delgado. She's a petite 14-and-a-half-year-old with a deadeye aim who works as a professional bounty hunter.
Bone: Gran'ma Ben is a great example of when this type of character grows up to be a Cool Old Lady, and retains all of her ass-kicking powers.
Bunty: Marie Bonnet of "Catch the Cat". She was a young girl who posed as a costumed person known as “the Cat" in order to resist the German occupation.
Cossacks: Zahra, a Tatar woman who joined the Cossack settlement. She's a fearless Master Archer.
De Kiekeboes: Charlotte, who followed a course in self-defense. Fanny too is a fighter.
Dreamkeepers: Just about every female character qualifies for this trope in some way.
In Prelude, Vi is quite possibly the most qualified. At least, if her ability to knock out a boy close to twice her size by doublefisting pillows is anything to go by. Apparently it isn't a very uncommon thing for her to go "Vi-Zerk", either...
One must also remember, however, that once she gets her powers (and even before) Namah is able to fight head-to-head with an experienced power user like Tinsel.
She also easily took out three Tower guards in Volume 3.
Duster (2015): Joanna Baker's job requires her to know how to pilot an airplane. She's also great with a gun and can pack quite the punch. As a result, she can beat trained Nazi soldiers.
Friday the 13th: Bloodbath: Once she gets her hands on a gun, Violet is pretty good at fighting both Jason and the corrupt government spooks, shooting down a helicopter at one point.
Echo: Ivy Raven, operative of the NSB, is the go-to agent whenever something needs to be tracked down, hushed up, or gotten rid of. Unless your yourself have access to a high-tech combat suit built of unobtainium, you should stay out of her way.
G.I. Joe: Scarlett, followed closely by Lady Jaye and even Cover Girl.
Group of 7: A Most Secret Tale: In Issue #5, when the team is about to be executed by enemy soldiers, their executioners are shot and killed by a female friend of Pearson's named Milunka Savic. She is stated to have fought alongside Pearson in Balkan, and survived against the German's feral Super Soldiers when they killed everyone else in her group.
Halloween Man: Lucy Chaplin, the titular hero's love interest, but also a non-costumed Bad Ass Normal superhero in her own right; she's a voluptuous, bespectacled and brilliant "weird scientist" who is also a crack shot and a well-trained martial artist. Lucy recently underwent a transformation into a mid-sized BBW at the hands of an rival (from "weird science university") Olympia Moreau. This has only made her a bigger (no pun intended) Action Girl, as Miss Chaplin gained aggression, height and considerable muscle mass to go along with her new, amply curvy flab (see Stout Strength). The latest adventure saw Lucy emphasizing her brawn and compensating for the reduction in agility with a mini jet-pack and a multi-ray gun.
Hard Graft: The comic features all round actiongirl (and madwoman) Bernadette Montez.
Hound: The Isle of Skye is home to warrior women, including Skye who owns a school training warriors from abroad. She defends her school from Eva's Kelpies with her followers and students.
Incandescence: Incandescence has been fighting people bigger than her since she was six.
Jet Dream: Jet Dream and the rest of her team of Stunt-Girl Counterspies.
Judge Dredd: The series has no shortage of very competent female judges. Notably Psi Judge Anderson and Galen DeMarco, both of whom got their own spin-offs.
Jupiter Jet: Jacqueline "Jacky" Johnson, who fights evil in her home city of Olympic Heights with a Jet Pack.
Kairos: Anaëlle not only fights several dragons at once, but even manages to stop a sword in mid swing with her bare hands.
Killtopia: All the female Wreckers count as this, but Stiletto is the number one Wrecker in Japan.
Megalex: Adamâ. She's beautiful and deadly, able to wield a gun quite well and also use a blowgun to kill armored robots by hitting their weak spot.
Modesty Blaise: Modesty Blaise, whom Jennifer K. Stuller (author of ''Ink-Stained Amazons and Cinematic Warriors: Superwomen in Modern Mythology) called "The most complex, sophisticated, skilled and intelligent of all action heroines".
Molly Danger: Molly Danger is a superheroine who's been protecting the town of Coopersville, New York for 20 years.
MonsterVerse: In the Kong: Skull Island direct sequel Skull Island: The Birth of Kong, Helen Karsten is supposed to be one In-Universe, but it doesn't amount to anything when she has her first (and last) creature encounter after arriving on Skull Island. The later graphic novel Kingdom Kong features multiple female Ace Pilots.
Nero: Madam Pheip and Madam Nero, who will defend their husbands and children whenever the chance is there.
Nikolai Dante: Elena Kurakin, a half-Mongolian swordswoman and Rudinshtein Irregular who killed her commanding officer for cowardice.
Nth Man: The Ultimate Ninja : Colonel Vavara Novikova, head of the KGB's Spetsburo (Assassination Bureau) and the second-deadliest assassin on Earth.
Omega the Unknown: One of the protagonist's surrogate parents fits this bill, being a savvy New Yorker living in Hell's Kitchen who makes money by following supers around and taking pictures of their battles for JJ Jameson, who she then argues with about compensation.
Painkiller Jane: Jane is a female version of the Punisher. In fact she even slept with him in a crossover. Her friends the 22 Brides are all experts in guns and killing things as well.
Preacher: Tulip O'Hare. She hates guns, except when they're shooting.
Primal Warrior Draco Azul: Ramona Escobar is introduced as a bartender whose father was a famous Badass Biker nicknamed El Gigante, who taught her how to handle herself in a fight. She demonstrates when saving Eric from some thugs, and after her bar is trashed by a Diablo she decides to join Draco Azul's crew and help the AI Ekchuah teach Eric how to properly fight.
Queen and Country: Tara is a skilled MI-6 operative who's good with both guns and unarmed combat.
The Rat Queens, the titular mercenaries/adventuring party from the eponymous comic book, are a party of these. Approximately 50% of all of Palisade's adventurers are women, including one all-woman group, one group with three women and one man, and one group with a single woman and three men. The only group without any women in it is the Four Daves, an all-male group where, you guessed it, every member is named Dave.
The Red Star: Alexandra Goncharova, Makita and Maya Antares.
Revival: Martha "Em" Cypress becomes one post-death.
Rogue Trooper: Venus Bluegenes, one of the very few GI Dolls to move into combat.
Sami The Samurai Squirrel: Sami defends the village of Woodbriar from all who would dare threaten it.
Sheena, Queen of the Jungle: Sheena practically set the standard for Action Girls! She even came before Wonder Woman! And was the first heroine to headline her own comic book!
Sonic the Hedgehog (IDW): Amy Rose, Blaze the Cat and Rogue the Bat, along with new additions Tangle the Lemur and Whisper the Wolf.
Spiritus: Kinju Dayal is a particularly brutal world-champion MMA fighter.
Star Trek (IDW): Uhura, who rescues members of the crew at several points throughout the series (and even has the opportunity to sit in the Captain's chair, though she refuses it and leaves McCoy in charge instead).
There's also Lieutenant Zahra. Kirk makes a point of taking her along on dangerous away missions
The rebel commander Mirith Sinn joined the Alliance after her husband was murdered by Darth Vader to make a point, and rose through the ranks until she in charge of a base on an Outer Rim world. And she is not shy in the least about getting her hands dirty. When things get desperate, she charges to the front lines, coldly dispatches Imperial guards, and even allows herself to be captured and tortured so an ally can escape. She even withstands the torture no matter how painful it got — until the enemy commander began an orbital bombardment of her troops' fallback position.
Star Wars: Invasion: Kaye Galfridian killed a Yuuzhan Vong warrior with nothing more than a knife, and later kills two stormtroopers with her bare hands. It's implied that this strength is due at least in part due to being an artificial Vong hybrid.
Suske en Wiske: Tante Sidonia can be inventive in tricking and fighting off her opponents too.
Teenage Mutant Ninja Turtles (Mirage): Midnight from the story arc "BodyCount" is a great example of a Badass Normal action girl; she is one of the best fighters in the story, able to beat a 300 pound giant of a man in unarmed combat and is pretty useful with guns and swords. It is worth noting that she was based off Julie Strain, Kevin Eastman's wife at the time.
Thin Blue Line: The Protagonist of the comic is Officer Maca, a Hispanic police officer in the city of Hagen, Illinois. She starts the comic winning a Brazilian Jiu-Jistu match, and over the course of the comic fights tooth and nail to keep the mayor, and herself, alive against a preverbial army of protestors out for their blood.
Tomoe Ame, who kicked the title character's ass as a kid.
Her cousin/ half-sisterNoriko the Blood Princess, who did the same to her.
Chizu, who qualifies by default as a Ninja and a recurring character.
Inazuma, the most skilled fighter in the book according to Word of God (with the possible exception of Katsuichi-sensei).
Kitsune does not exactly qualify (preferring stealth to more direct approaches), but has been shown to have some skill with swords/battle tops/knees...
Whisper: Alexis Devinn. She was trained in the ways of ninjutsu by her step-father, Jiro Hatzumi from childhood. She also seems to have kept her skills sharp into adulthood, which allowed her to be able to power through great pain and throw down with a bunch of armed guards, as well as interrogate a Yakuza boss by threatening to drown him.
An unnamed miller's daughter in a story by Wilhelm Busch. She's alone when three robbers enter the mill, one of them implied to be a rapist. But without feeling in trouble for a moment, she flattens the wannabe rapist with a millstone, rolls up the second robber to a spiral (with the help of the turning axis of the mill-wheel), and beheads the third one (who apparently doesn't care for the fate of his mates) when he tries to rob the gold from a chest. The author comments: "This is how one single girl gets three men into trouble." Read it here.
Witchblade: The titular weapon tends to take female hosts, granting them great power.
Plourr Ilo. Just look◊ at her! She is a princess and her story is loosely based on that of Anastasia, but she is also a competent mechanic and pilot, a bit of a Tsundere, and both strong and good at hand-to-hand combat.
Elscol Lora, a highly trained commando who leads operations against the Empire along with two ex-Imperials who defected.
Feylis Ardele gets distinguished as a highly competent fighter either in her X-Wing or on the ground.
Overall, any female pilot in the unit has to be one by default.
Y: The Last Man: Agent 355 (and most of the rest of the Culper Ring). A good thing too, as the eponymous walking MacGuffin is a definite Non-Action Guy. Natalya Zamyatin also fits the bill, as does Hero Brown after her Heel–Face Turn.
