- "Funny Aneurysm" Moment: The episode ends with Rene, Picard's nephew, declaring that someday, he'll enter Starfleet, following in his uncle's footsteps. In Star Trek: Generations, we learn that Rene, as well as Robert, both burned to death in a fire at the vineyard. What's worse is that the closing shot in "Family" has a burning fireplace in the background!
- Growing the Beard: While the show itself had been improving for some time, a great many fans think this is the episode where it happened for the character of Picard and where Sir Patrick Stewart elevated him to the best of the Trek captains. It gave Picard a far greater amount of emotional depth and informed his character for the rest of TNG's run.
- Harsher in Hindsight: The portrayal of Picard's issues with his father and his post-traumatic stress disorder from his Borg assimilation. Years later, Patrick Stewart revealed that his father suffered from PTSD after his service in World War II, which wasn't understood at the time and went untreated, causing him to become abusive towards his family.
- In this episode, Picard is so shaken by being assimilated by the Borg that he considers leaving Starfleet. In Star Trek: Picard, it's revealed that Picard has left Starfleet due to his failure to save Romulus from the supernova of 2387.
YMMV / Star Trek: The Next Generation S4E2 "Family"