- He's Just Hiding!: If Fitz's past counterpart is a Human Popsicle somewhere out in space, then it stands to reason that Enoch is out there as well, still very much alive and seeking to continue his mission of observing humanity despite his (now averted) Heroic Sacrifice in the Bad Future back in the mid-season finale.
- Inferred Holocaust: The episode wraps up before the final ramifications of Avengers: Infinity War can take place, leaving the fates of the entire cast up in the air.
- Last word was that Season 6 would air during the Summer of 2019, after the conclusion of the Infinity War story arc.
YMMV / Agents of S.H.I.E.L.D. S5E22 "The End"