- Actor Allusion: This isn't the first time Jake Gyllenhaal gets severely wounded next to his eye while confronting and killing the Big Bad of the film. Detective Loki fared much better than Tony Hastings, though.
- Acting for Two: Jake Gyllenhaal plays both Edward Sheffield and Tony Hastings.
- Casting Gag: Susan's obvious expy in the book, Laura, is played by Isla Fisher, whose uncanny resemblance to Amy Adams has become a popular Internet meme. There's no way that casting Isla Fisher in the role is a coincidence.
- Creator's Favorite Episode: The films director of photography Seamus McGarvey considers this to be his favorite work hes ever done on a project.
- Fake American: Brits Aaron Taylor-Johnson, Robert Aramayo and Ellie Bamber as Ray Marcus, Turk and India Hastings respectively; and Australian Isla Fisher as Laura Hastings.
- Playing Gertrude: Laura Linney plays the mother of Amy Adams - who's only ten years younger.
Trivia / Nocturnal Animals