- The ending of the anime. Then the ending of the OVA just to top themselves on sadness.
- The episode where Mitsuko reunites with her mother. And her mother's tearful suicide in front of her children, after realizing she really did care for them.
- The woman who is forever waiting for the man to come back to her, not realizing he's already dead.
- Rieko's death. And then Ichiro's. And Rei's. And Bijinder's.
- Jiro's speech in the last part of the OVA and the accompanying music is heartbreaking.
- For the live action series, the deaths of Gold Wolf, Jinbei, the two Spiny Anteaters and Saburo/Hakaider.
Tear Jerker / Kikaider