Krang and Shredder are at war with the Neutrinos, and their leaders have sent their baby to Earth for the turtles to look after.
Tropes:
- Mind over Matter: Neutrinos are born with telekinesis and lose it as they get older, a problem the turtles and April have to deal with while they're looking after Tribble.
- Pop-Culture Pun Episode Title: The title is a reference to Three Men and a Baby.
- Remember the New Guy?: This is the first time Gizzla and Zenter, monarchs of the Neutrino race, ever appear, yet the turtles and Shredder already know them.
- You Didn't Ask: When Shredder asked why Krang didn't tell him that Neutrino babies had Psychic Powers, Krang says "I didn't want to worry you."