History HalfHumanHybrid / WesternAnimation

* ''WesternAnimation/AdventureTime'': Marceline was born half-human, half-demon. She became a vampire when she was a teenager.

* ''WesternAnimation/Ben10AlienForce'' has Ben training a band of kids with powers similar to his original aliens (or at least he SHOULD be training them, but the animators don't seem to want to have to draw massive amounts of cast members each episode, so the status quo of three is maintained) to fight the alien BigBad. Interestingly, these kids are all hybrids of aliens of varying species and children of Plumbers (who have all been given badges that act as tracking devices, making them easy to find), which makes you wonder if an interest in alien reproduction is a requirement to join the Plumbers... And the fact that a human shouldn't even be able to touch an alien made of lava can be handwaved with the use of alien technology, should any fan get a case of FridgeLogic.
** Manny is half-Tetramand (Fourarms' species), Helen is half-Kineceleran ([=XLR8=]'s species), and Alan is half-Pyronite (Heatblast's species). While Alan can switch between his human and alien forms, Manny and Helen stay looking like Kineceleran and Tetramand. [[spoiler:Omniverse retcons this. They weren't born hybrids; they were ordinary human kids who had their DNA mixed with aliens.]]

* In the finale of ''WesternAnimation/TheOwlHouse'', [[spoiler:Luz becomes a human/titan hybrid thanks to the Titan's spirit giving her his remaining life force to help revive her. In addition to altering her appearance to more closely resemble King, it grants her all forms of magic found on the Boiling Isles (spell circles, summoning glyphs with a thought, and King's roars) on a level far above anything else seen in the series. However, once the last of the Titan's life force leaves her body she returns to being an ordinary human with no lingering effects.]]

* ''WesternAnimation/TransformersAnimated'': [[spoiler:Sari Sumdac]] is half human and half ''Franchise/{{Transformer|s}}''. She's essentially a [[WesternAnimation/BeastWars Maximal]] with a human as her beast mode.

* ''WesternAnimation/TransformersAnimated'': [[spoiler:Sari Sumdac]] is half human and half ''{{Transformer|s}}''. She's essentially a [[WesternAnimation/BeastWars Maximal]] with a human as her beast mode.

*** [[Recap/StarWarsTheCloneWarsS2E10TheDeserter "The Deserter"]] involves a [[GreenSkinnedSpaceBabe Twi'lek]] woman and her two half-human, half-Twi'lek children as major characters [[spoiler:her clone trooper husband being the titular deserter. Though notably, he isn't their biological father]].

* ''WesternAnimation/TransformersAnimated'' [[spoiler:Sari Sumdac]] is half human and half ''{{Transformer|s}}''. She's essentially a [[WesternAnimation/BeastWars Maximal]] with a human as her beast mode.