Alternative Character Interpretation: The movie seems to imply that the real reason for Ramius defecting was less anger of his wife's death and more concern over the fact that the Red October's primary purpose would be to start a nuclear war due to its stealth. In that context, Ryan's comments about Ramius's wife are more that he no longer has any reason to go back home.
It could also be said (based on both the book and the film), that the death of Ramius' wife by an incompetent/drunk, Party-connected doctor got him 90-95% of the way there, then seeing the plans for the Red October filled up the defection meter the rest of the way, as he recognized how destabilizing this new sub design would be for world peace.
"This business will get out of control. It will get out of control and we will be lucky to live through it."
"Give me a ping, Vasily. One ping only, please."
Narm: To some native Russian speakers, Sean Connery speaking Russian in his trademark Scottish accent is hilarious. Also, Alec Baldwin's American accent when speaking Russian is so thick as to be unintelligible.
One-Scene Wonder: Rear Admiral Painter (played by actor and Tennessee senator Fred Thompson) has a small, but very memorable role in the film.