These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Base Breaker: In this day and age, Pepe is hated by Moral Guardians and some fans due to Values Dissonance (see below) and his shorts being formulaic. Those who don't hate Pepe see him as an Ensemble Darkhorse because the values dissonance of his cartoons presumably represent how free and audacious cartoons were back then compared to the ones made now.
Bizarro Episode: "Odor Of The Day" is completely detached from the standard formula, with Pepe (a mostly Silent Protagonist here) instead in a feud with a dog over shelter in the snow. The animation and visuals are also far different from Chuck Jones' usual style, due to being created by Arthur Davis' unit.
Values Dissonance: Egads, these cartoons haven't aged well (in terms of moral values) since the 1940s. In this day and age, Pepe would totally be branded a stalker-cum-rapist (this was lampshaded on Dave Chappelle's infamous bit on Killing Them Softly about how most TV shows you watched as a child have a dark side to them when you grow up). On the flipside of this, there are some Looney Tunes fans who enjoy the Pepe cartoons more when they're older thanks to this interesting bit of Values Dissonance (see Base Breaker above).
Probly best represented with a bit of fan art from the late 1990s, where Pepe is hugging a resisting Penelope, whereupon he receives a sexual harassment lawsuit notice from a human lawyer.
"Weird Al" Effect: Not that many people know this, but Pepe Le Pew was based on Charles Boyer's character Pepe Le Moko from the movie Algiers (which was actually referenced in a background gag on "The Cats' Bah").
Another "Weird Al" Effect: The beginning of "The Cats Bah" is a parody of the original 1950s TV version of The Continental (way before Christopher Walken would make a recurring sketch out of it on SNL).
The Woobie: Penelope, and any other cat character who has had the misfortune of being painted in skunk colors and left to be harrassed by Pepe. In cases such as "Odor-able Kitty" and "Scent-imental Over You" the victims actually had pretty bad before they even met him.