YMMV / Ozzy & Drix

• Accidental Aesop:
  • "Dream Factory" doesn't have a clear Aesop about health like most others, but it could be read as the show's Sleep Aesop since Hector's lack of sleep does cause problems (his lack of focus almost gets him run over in one scene). The difference being that, unlike most Aesop episodes, the lack of sleep isn't Hector's fault (it's from a reoccuring nightmare as opposed to, for instance, him staying up late playing video games or having to pull all-nighters to complete schoolwork he procrastinated on).
  • On top of the typical "No Smoking" aesop, "Where There's Smoke" could also carry an Aesop against caving to peer pressure, and that people who actually care about you wouldn't push you to do anything harmful.
• Adaptation Displacement: Downplayed. While the original Osmosis Jones film is a Cult Classic, it was also a Box Office Bomb due to Warner Bros. Executive Meddling that resulted in an unfocused film, with the Invisible Advertising not helping matters either. As a result, there are some fans of this show that aren't aware that it's supposed to be a spin-off until much later.
• Alternate Character Interpretation: In "Gas of Doom", after Hector releases the titular gas and Christine, as planned, blames the smell on a nearby compost pile, Hector leaves and Christine's friend asks her if she "just cut one with Hector standing right next to [her]?" Christine hesitates for a second before answering in the affirmative. Did she really have her own case of gas at the same time as Hector (not implausible given the 12-bean salad the cafeteria served for lunch that day—her friend even comments afterward that she warned Christine against eating it), or was she just taking the fall for him to spare him the embarrassment?
• Anvilicious: The show is not subtle about the health and safety advice it gives, but since it's meant to be an edutainment show about a teenager's body, it can be forgiven for this.
• Awesome Music: The theme song definitely qualifies.
  • Any song sung by Metabolica qualifies but "Hector's Toast" from "Bad Reflex" is a real standout.
• Broken Base:
  • Whether the show is a sequel to the film or some sort of alternate universe. In the first episode, Frank is shown living in a trailer instead of a house and his daughter Shane is nowhere to be seen.
  • Some fans see the series as better than the movie due to the omission of live-action grossout scenes and its edutainment factor, while others see it as inferior to the movie and expressed disappointment that the darker, "adult" tone of the movie was replaced with a lighter, cheesier, more kid-friendly one in the show.
• Evil Is Cool: Nick O'Teen has a badass design, is a genuinely menacing villain, is voiced by Tim Curry, and sings a Villain Song backed by Captain Ersatzes of Metallica. What's not to love?
• Fandom-Specific Plot: It's a little niche but there are more than a few fans who love the idea of Ozzy and Drix co-parenting Spryman and trying (mostly successfully) to unspoil him. Content generally features Ozzy and Drix being Good Parents and Spryman (referred to as either just Paul or Paulie) eventually coming to appreciate them as parental figures. A sub-variation of this involves Spryman being removed from office somehow (whether because his incompetency finally catches up with him or because he just gets voted out) and when Ozzy and Drix see his utter defeat and lack of purpose once no longer mayor, their parental instincts kick in and they play mentors.
• Fanon: "Double Dose" is kicked off by Ozzy dividing in two during a nightmare, specifically one recreating the Bugs Bunny Cartoon Hair-Raising Hare. However, the shot we get of him reacting to it — writhing fitfully in bed, punching the pillow in his sleep, and then splitting in two — has led to the fandom to speculate that it actually happened during a different nightmare, one where he was reliving his battle with Thrax.
• Genius Bonus: The episode "Strepfinger" is a James Bond pastiche featuring a penicillin drug portrayed as a Tuxedo and Martini secret agent. It seems like a random gag, unless you know that penicillin was discovered by a scientist named "Fleming".
• Hilarious in Hindsight: During the Cold Opening of "Gas of Doom" Metaboloica's leader calls Ozzy a "Guitar Hero". The first game wouldn't be out for another 3 years when this episode aired.
  • In "An Out Of Body Experience" a control panel is shown inside Hector's mind with his various fears. This brings to mind a certain Pixar movie released 11 years after this show ended.
• Jerkass Woobie:
  • Ozzy's evil twin in the episode where Ozzy undergoes mitosis and splits into two. While his motives don't justify trying to kill Ozzy, he notes that his mutation will lead to him being rejected by Hector unless he kills the original, meaning he's basically motivated by a fear of dying so soon after he came into existence. Even Ozzy himself seems to sympathize, as he arranges to have his twin sent to Hector's dog to be "King of the Canine" rather than just straight up flushed.
  • Some fans actually view Spryman this way; yes he's a Bratty Half-Pint Ungrateful Bastard Spoiled Brat but we never see his parents so it's entirely possible he was or at least is currently being raised by a bunch of Yes-Man politicians who give him whatever he wants to shut him up so they don't have to deal with him and his bratty behavior is the result of being a teenager without any proper adult guidance. Contrast him with Hector, the teen whose body he's in charge of, who is a much more likeable kid and it's clearly due to his Good Parents.
• The Problem with Licensed Games: The only impressive thing that could be said about the Game Boy Advance game is that it managed to use real-time rendered 3D models for all the characters throughout the game. Everything else is a complete and utter snore fest, lacking any variety between Osmosis and Drix, bland, repetitive music, and loads and loads of Fake Difficulty caused by stiff controls that may not even register your inputs half of the time.
• Strawman Has a Point: Both Chief Gluteus and Mayor Spryman tend to give Ozzy, and to a lesser extent Drix, a hard time when it comes to their involvement in trying to take down the germs and viruses that want to harm Hector, as they both don't get much respect or gratitude for the rounds up they make, and have been blamed a couple of times for things that weren't their fault. But considering that Ozzy tends to cause trouble for both Gluteus and Spryman a lot, he is often disrespectful to both of them especially when he met them in the first episode, and since he and Drix are both detectives and their involvement in police work comes off as vigilantism, it's justified why he and Drix don't get much respect from them.
• Tear Jerker: In "Tricky Ricardo", after kicking her estranged, troublemaking brother Ricky out of her apartment, Maria breaks down in Drix's chest, heartbroken over the life her brother has chosen to live.
• The Woobie: Poor Hector had the misfortune of having his body be the main hub of a show about health and the human body...so naturally he's the host to a whole bunch of illnesses and injuries, many of which could kill him. And unlike Frank, he's just a teen. To top it off, while some of what he does go through were logical, if exaggerated, end results of his actions in order to teach An Aesop (the episode about a blood clot implied he'd been eating unhealthily for a while now, the episode about a concussion started with him skateboarding with no helmet, etc.), some were just bad luck or circumstance (the pilot episode shows him getting Scarlet Fever from a mosquito bite, and the very next episode is him having to face a bully who could knock six bells out of him because Ozzy hit the wrong nerve at the wrong time).

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