Hey, It's That Voice!: (Quoth X-Entertainment: "If you're new to the show, it'll take awhile for you to stop expecting lasagna jokes [from Peter, who is voiced by Lorenzo Music in the early half of the show's run].")
It becomes Hilarious in Hindsight, because in 2004, a live-action Garfield movie would be released. In that film, Garfield is voiced by Bill Murray, who played Peter Venkman in the Ghostbusters movie.
Because Bill Murray complained to the producers that his character "sounds like Garfield", they replaced him with Uncle Joey (Dave Coulier).
The Slimer! shorts featured Cree Summer as Chilly Cooper, an ice cream truck driver who befriends Slimer.
Crowley from "The Halloween Door" was voiced by Michael Rye, better known as Duke Igthorn.
Cree Summer played Chilly Cooper from the Slimer! and the Real Ghostbusters era.
The Other Darrin: After the syndicated episodes, Dave Coulier replaced Lorenzo Music as Peter and Kath Soucie replaced Laura Summer as Janine. A season later, Arsenio Hall left for his talk show and was replaced by Buster Jones.
In the second season, whenever the Stay Puft Marshmallow Man appeared, Frank Welker handled any vocal effects. In Season 3's "Sticky Business," John Stocker took over the role. Later in Season 5's "Partners in Slime," Welker again voiced the character for a brief cameo.
Promoted Fanboy: A number of people involved at the start of production were fans of the movie. Maurice La Marche is one such example.