Doc: I'm trying to think of that thing I said earlier today, when I was riding that raptor there, and how Death was mad at me... and somehow I applied it to you? I forget it now. It would have been good. But, uh, whatever. You're like, the lamest Great Dane since Marmaduke, and I'm gonna kill you. Whatever, who cares. Let's go.
Doc: Hello. My name is Doctor McNinja, and I'm going to be your phlebotomist today. Random mook: Wot's a phlegm botanist? Doc: It means I'm going to draw your blood.
Mitzi McNinja gets one of her own during the "Punch Dracula" Story Arc: "And the dead can't hear their own eulogies. So let's wrap this up.!"
In the Axe Cop crossover, when Axe Cop summons a giant robot suit to fight the bad guy with:
In Girl Genius Gilgamesh Wulfenbach does pretty well here (starting with the last panel, and continuing the rant through a few pages of the brawl), then attempts one here but fails. Tarvek here reminds us he's trained as a SmokeKnight.
In Brawl in the Family, during the Phillips CD-I arc, Waluigi returns from vacation to find a Phillips CD-I making everyone become characters from that game... except Dedede, who's trying not to go insane. He views the situation, and then says "Weh. You call this madness? Step aside.Waluigi time."
Head Alien: "Once again, only one of us leaves alive."
Sal: "Or neither. Ah ain't picky."
Axe Cop, in the guest story "Revenge on Rainbow Girl", faces off with a giant dragon and says "I'm sorry, but this is too late for you" before attacking. If you're wondering, it's a direct quote from a child's narrating the scene.
L's Empire has this one after some Whackas have been trapped by an angry Physical God. He doesn't get to follow through on it due to being on probation.