And not just the anime either. He bites the dust in most of his appearances in Super Robot Wars as well. Very, VERY rarely is he savable. However, despite being savable in Alpha 2, his death is Canon.
There seems to be a Recurring Character in Mobile Suit Gundam Wing, who's almost always the Mook leader, that dies all the time during the latter part of the series. On a side note, he may also be the one that ends up shooting Dekim in the head from the sound of his voice but that's probably due to recycling VAs rather then intentionally.
Leomon from Digimon is a special case. Every series but the second and seventh is a hard reboot, and all Mons of a type are identical, so there are several guys named Leomon or SomethingLeomon who are not the same guy, or even Alternate Continuity versions of the same guy. And what happens to them?
Digimon Adventure: Leomon eats a blast meant for Mimi, and after helping vanquish the villain, bites it.
Digimon Tamers: Leomon becomes Juri's partner, and eventually gets run through and absorbed by Beelzebumon, sending Juri over the Despair Event Horizon and setting the stage for D-Reaper's use of her.
Digimon Frontier: JagerLowemon's Japanese name? KaiserLeomon. Actually being human doesn't save him from death at the hands of Lucemon, though it turns out that like Shibumi of Tamers, he's actually physically in the human world and his mind is connected to the digital world, unlike the others. He's alive and well when they get home. Bonus points for a Monster of the Week, Panjamon, who is a white recolor of Leomon. He gets taken out quite easily, but since he's in Mercuremon's illusionary world, and leaves no egg behind, he may never have been real.
Digimon Savers: SaberLeomon is a "good but misguided" type who believes humans are bad due to the bad actions of one guy. Not only does he die, but... in all Digimon series but Tamers, Digimon revert to an egg state and begin life again, never truly dying. However, Kurata figures out a way to corrupt a Digimon's data so that it can never be revived. SaberLeomon is the first Digimon in this series to die permanently. Also, BanchoLeomon turns out to be holding the spirit of the lead character's father. Naturally, he dies too. When the reformed Big Bad gives Daddy back, nothing is said about BanchoLeomon. Harsh.
Digimon Xros Wars: MadLeomon is a villain general. The first one. As he's a Warmup Boss, he's offed very quickly. And he's not the only one; later on there's Apollomon, who while not sharing the name is definitely leonine. He dies twice, but is revived at the end of the series.
And then there's Digimon X-Evolution, where a Leomon dies in the first three minutes. And because he considered the digimon he was attacking (the main character) more worthy of being alive!
Vrumugun from Slayers appears in maybe eight episodes, and dies roughly a dozen times over the course of them. In the anime, this is because he has been repeatedly cloned. In the novels, this is because the 'Vrumuguns' who are killed are actually people being magically controlled by the real Vrumugun.
Chuck the ghost dog from Panty & Stocking with Garterbelt is killed multiple times in every episode only to reappear at random times alive only to get killed again.
Although everyone in Angel Beats! dies repeatedly, none of them dies as often as Noda, whose appearance WILL guarantee death.
JoJo's Bizarre Adventure has the Zeppeli family, in Parts 1 and 2, which has both of their members ( Will A. Zeppeli and Caesar Zeppeli die against one of the major enemies but managing to inspire the protagonist beyond the grave. Gyro Zeppeli from Part 7 does not escape the same fate.
Carnival Phantasm has Lancer, who seems to die in his every appearance. In fact, he once got spontaneously struck by lightning on a clear day, and was even eaten by Saber in a lion suit. The Beach Episode is the only episode where he doesn't die because he doesn't show up there. Episode 11 remedies this by revealing that he was hiding in the rocket when it got punctured by a ballistic volleyball.
More famously, there's Squee, who eventually proved to be so popular he got his own card, complete with a returning-to-play mechanic.
"He is Yawgmoth's reward to me. I shall kill him a hundred times a day."
More recently, the card Reassembling Skeleton lampshades a lesser-known rule regarding creature cards; If a non-token creature leaves play for any reason but returns at some point, the game state considers it a different creature. To sum up, same card does not equal same creature.
Chaotic has similar flavor text for some cards involving Bodal.
An interesting variation in the succession of Grasshoppers that join the same team; none of them are the same character, but all of them take the hero name Grasshopper, join the team to replace the last Grasshopper, and then get killed in various ugly ways, each with less panel time than the one before.
The MAD Magazine comic Spy vs. Spy features a black and a white spy trying to outsmart each other, and either one of them usually ends up beaten or dead by the end of the strip, only to be alive and well by the next gag.
According to Word Of God from creator Antonio Prohías, they are not the same spy, but are instead merely spies from rival nations that die horribly and are replaced — this was the basis of his commentary on the Cold War.
There is also a sub-set of Spy vs. Spy vs. Spy strips which generally end with both the black and the white spy being dead, outwitted by the (female) grey spy.
Emperor Palpatine in Dark Empire. Practically everyone kills him. Mostly Luke and Leia. Han kills him the last time.
Due to a combination of Black Comedy and Negative Continuity, nearly the entire cast of Twisted Toyfare Theatre, or at least the setting Megoville, dies several times over the course of the series. The character guides in the trades frequently list several deaths for each character. Bucky probably dies the most consistently.
It's well known among Transformers fans that any character without a toy is a Red Shirt. The Transformers Armada comic series had a recurring Red Shirt in Dropshot, whose design was taken from a Japanese transforming robot that was not imported during the original series' run.
The Decepticon Dirge is in any number of unconnected comic series, and meets his doom in nearly every last one, and blows up twice in the G1 cartoon. His death count may be higher than Prime. The TF Wiki quotes his Badass Boast, "Death comes to he who crosses me!" and attributes it to "a confused Dirge."
Averted in Transformers Robots In Disguise: Which is one of the few series (possibly only) where he becomes an important character, and avoids fatal circumstances (at least twice by now)
The Decepticon Quake is also fairly death prone.
One of the comic series plays with Optimus' tendency to bite it (see the Western Animation folder) by titling a special issue The Death of Optimus Prime. For once, it's metaphorical; Optimus is freed from the burden of leadership and declares That Man Is Dead, returning to his original identity of Orion Pax.
DC's Solomon Grundy is a cursed zombie (sort of), so whenever he dies he just rises again from the same swamp he died in (often with a completely new personality, including some times where he's been heroic), which of course happens all the time. Eventually they just strand him on an uninhabited planet.
A number of characters in Viz have died and come back without explanation, but Suicidal Sid and Big Vern (and his supporting cast) die almost every time.
The Finnish western comic, Pekkos Bill, have the titular hero dying violently in every third panel, always with the same smug expression on his face (unless the death involves the obliteration of his head or entire person).
Iznogoud, in his plots to overthrow the Caliph, always ends up locked in a dungeon, permanently transformed, vanished, etc. and is back to resume his plotting at the beginning of the next episode.
In Sandman, the Dream's retinue includes Kain and Abel. Since they are technically an Anthropomorphic Personification of the idea of fratricide, Kain kills Abel almost every time they appear in the comic, in various ways (most infamously, mincing him into sausages as part of a stage performance for the visiting gods.)
In the Final Fantasy fanfic Cid Wars, Biggs and Wedge are killed every time they show up, amounting to at least a dozen times over the course of the fic.
A Fan Fiction.Net author by the handle of Carbuncle frequently kills off Aeris in his Final Fantasy VII fanfics, which is followed by exclamations of "Oh my god, they killed Aeris!" "You beasts!" This is an obvious reference to Kenny's deaths on South Park.
In Chris McFeely's later Digimon fics, the series' running gag of Leomon dying becomes this.
Dirge in the Transformers fic, They Just Don't Care Anymore, dies in almost every chapter, even parodied in the Halloween Special, where he dresses up as Kenny and, predictably, dies.
He fares no better in canon.
In the Ed Edd N Eddy fanfic YouTube Ed, after chapter 6, Eddy gets brutally killed in some sort of way. Edd and Edder then give an obvious South Park reference, as seen below. This was actually required in one chapter to find Edder, though the kids found out it was a trap for them the whole time.
Edd: Oh my goodness, they killed Eddy! Edder: You bastards. Ed: I see an obvious crossover here!
In The Emiya Clan, Lancer gets this shoved upon him at every possible point. It got to the point where AU!Illya and Zelretch were summoning him just to see how many strange and peculiar ways they could make him suffer.
Also, an army of Lancers makes for a great supply of expendable labor.
As of the prologue of Episode II, it's been confirmed that he survived the Battle of Krantisi and has been promoted to Sergeant. Doesn't seem like he's going to die as much as he used to, especially since he didn't die at the end of his first scene of the Episode.
Also, Zolph has stopped trying to figure out how he keeps coming back despite total obliteration after trying to ask him the one time it seemed absolutely safe only for him to be killed randomly before answering. He now just assumes The Force is resurrecting Helms for its own sadistic amusement.
Also, he has confirmed that the first time he died was before he was even born. Don't worry, he had a good childhood after birth (aside from a few accidents he got himself into).
In Little Nicky the title character is killed a total of seven times throughout the movie. As a son of the Devil, he has Justified Extra Lives and can just walk out of Hell. First, he gets hit by a train two seconds after arriving on Earth. Then he gets hit by a bus, attacked by a polar bear, hit by a truck, drowned by his roommate and stoner friends (at his own insistence), and hit by a train again while protecting his girlfriend - which, as as selfless act, sends him to Heaven. Finally, Valerie smashes his skull with a boulder given to her by Ozzy Osbourne so he can see his dad one last time.
In the first, second, and third Scary Movie films Brenda gets killed and she's always back for the next one. The fourth one she actually survived. In a scene available in the DVD she is celebrating finally not being killed off in the movie, then a cargo container falls on her.
In the first two Men In Black movies, the local alien black market dealer Jack Jeebs serves a humorous variant on this trope in which his head is blown off, only to re-grow within less than a minute. This happens multiple times in both movies, usually with the MIB themselves perpetrating the deed, much to his frustration ("You insensitive pricks, do you know how much that stings?").
Jeebs: Even if I did, if it doesn't work, K dies, you blow my head off. If it does work, I brought back K who, just for the fun of it, blows my head off. Sooo, what's my incentive? [K raises his gun to Jeebs' head] Jeebs: [Weak laugh] Okay homey, I keep it right downstairs next to the snow blower.
A long-running joke like this is hard to pull off in a film-format, but Top Secret! manages with the character of Latrine, who shows up three times, mortally wounded, to gasp out the intelligence he gathered.
In The Gamers: Dorkness Rising, the bard user gets sick of being resurrected (and subsequently losing a level)... so he brings in 50 more bard character sheets. In one scene, the other characters literally use his pile of corpses as cover.
Phil in Groundhog Day is living the same day over and over due to a time paradox. He finally loses it, abducts the town's groundhog and kills himself by driving off a cliff, only to wake up alive and well the "next" morning. He then spends a long time committing suicide, trying to find a way out, only to keep waking up unharmed the "next" day. While the audience only sees a handful of the attempts, he later talks about his predicament to another character and runs down a verbal list of all the various ways he's killed himself.
Scamper the rabbit from Igor is killed multiple times but always comes back because he was injected with an immortality potion. At one point his head is blown off but it just regenerates; a recurring gag is how he just wants to die permanently.
Scruffy Banister the cat from Madhouse died about 7 times in the movie: its deaths include getting hit by a car, drowning in a fish tank, hit by a lawn mower, blown up by a firecracker, and dying of a heart attack after snorting cocaine. This is probably because of the myth that cats supposedly have 9 lives.
Loaded Weapon 1 has a character that keeps returning after his death because he thinks it's the sequel already.
The Three Stooges die at the end of four of their shorts "Half Shot Shooter", "Three Little Sew and Sews", "You Nazty Spie!" (later revealed to have been averted in the sequel,) and "I'll Never Heil Again".
In Joel Chandler Harris' original Uncle Remus stories of Brer Rabbit and company, characters sometimes were said to be actually killed by the actions of Brer Rabbit or the others. In the first volume of stories, Brer Possum burns to death during a 'trial by fire' in Brer Rabbit Nips the Butter, Brer Wolf is locked in a chest and scalded to death in The Awful Fate of Mr. Wolf, and Brer Fox is killed by a farmer and decapitated in The Sad Fate of Mr. Fox. But all are back alive again in the second volume, Nights With Uncle Remus thanks to the Negative Continuity of the stories. Brer Wolf, in particular, is done in again several times in the second volume, and again back as if nothing happened.
In fact, Brer Wolf is back in a later story in the first volume, How Mr. Rabbit Saved His Meat, which lampshades this. The little boy to whom Uncle Remus tells the stories to objects when Uncle Remus introduces Brer Wolf, saying that Brer Rabbit scalded the wolf to death. Uncle Remus is forced to admit that yes, that's what happened in the earlier story, and that the story he's telling now might take place before it happened or be about a different Brer Wolf. He doesn't really know — he just tells them the way he hears them. And that's his final word on the matter and he goes on with the story.
Commissar Ciaphas Cain (HERO OF THE IMPERIUM!) has been mistakenly reported dead so many times that there is a standing order that he isn't to be taken off the active duty list. Inquisitor Vail notes in the commentary that he is the only officer in the history of the Imperium to remain on the active duty list a hundred and fifty years after being buried with full military honors.
In Daniel Pinkwater's Young Adult Novel, installments of the story within the story "Kevin Shapiro, Boy Orphan" are said to frequently end with Kenny's unceremonious death. Charles the Cat explains: "Kevin is indestructible. You can kill him as often as you like. He can be brought back to life in the next chapter, which usually gets told the following day during lunch."
In the series of Clue books, Mr. Boddy was always "killed" in the final chapter. He would then explain how he survived in the introduction of the next book, usually by some silly, implausible stroke of luck (i.e., his murderer accidentally picking up a banana instead of a revolver).
While only one died, teaching Defense Against the Dark Arts at Hogwarts is not good to anyone's health. No wonder Dumbledore didn't find someone to take the job in the fifth book.
Well, let's see... One died, one got his memory permanently erased, one quit because of an oncoming scandal due to his Lycanthropy, one got shoved in a trunk/bag of holding for nine months by an impostor, one was run out of the school by essentially an open rebellion of the students and a poltergeist, one was part of a VERY complex double agent plan for Voldemort, and the last one died/went to Azkaban after the Battle of Hogwarts.
No one ever holds the job for two consecutive years since Voldemort tried - and failed - to get it. Something always makes them leave. The one who died was said to have taught Muggle Studies in prior years before taking a sabbatical to get more experience.
Dinosaurs had a Show Within a Show called Ask Mr. Lizard. The young volunteer, Timmy, would die as a result of the science experiment every episode, prompting Mr. Lizard to spout his much anticipated Catch Phrase, "We're gonna need another Timmy!"
A recent example on SNL is Bobby Moynihan's "Ass Dan" character, who has been declared dead in 2009, but has come back (and died again) in 2010 (twice), and 2011.
Not necessarily a Running Gag or any sort of comedic effect, but Ensign Kim from Star Trek: Voyager seems to fit for this. Basically put, Ensign Kim is the series' designated Red Shirt and any time he and one other person are on an away mission, you can almost guarantee that Kim is going to bite the big one... again. Of course, he comes back rather easily with all the various temporal stuff, cloning, alternate dimensions, and just damn good medical stuff.
Female Changeling: "I wish you hadn't done that. That was Weyoun's last clone."
Garak: "I was hoping you would say that."
It's been removed now for being too interesting, but at one point the Wikipedia page on Charmed had a tally of how many times the sisters had died. They were all in double figures.
In The Middleman there are the various Interrodroids, and to some extent Ida.
Larry Duff from Father Ted. Whenever Ted calls his mobile, he's in the middle of doing something from which he really doesn't want to be distracted. The resulting accidents are never shown to be fatal, but he probably qualifies for the trope anyway.
Spoofed, along with the Red Shirt, in an episode of My Best Friend Is An Alien, in which the combination of Fan Dumb and VR results in the school being turned temporarily into an episode of Tarbox Moon Warriors (an in-universe show everyone except the main character hates). Said main character comments that "the ensign in the orange shirt" is killed every episode.
On Misfits, after Nathan's power is revealed to be immortality, he begins to die frequently in a variety of gruesome (and often comedic) ways.
The henchman called "The Cleaner" in Primeval. It turns out that he's actually a bunch of clones.
In the episode "Welcome Back Carter" (EUReKA), the new robotic sheriff Andy is crushed multiple times, but Fargo always seems to be able to fix him, though with varying malfunctions occasionally popping up.
He comes back as Jack's new deputy in season 4, and goes in for repairs a lot.
The Doctor, and other Time Lords, can regenerate into a new person every time they die, hence "The Nth Doctor" being the name of the trope. It's happened to him 10 times so far.
Rory Williams was killed or thought to be killed so many times in the space of less than 2 seasons that it was lampshaded in "Night Terrors." Rory and Amy were transported to a dark room and Rory said, annoyed, "We're dead... We're dead, AGAIN!" It's Lampshaded again in "The Wedding of River Song." Apparently, aliens have a new title for Rory: "the man who dies and dies again." It's also led to the meme 'OH MY GOD, THEY KILLED RORY!'
In Rory's final episode, he dies no less than three times. And two of those were from old age.
Clara Oswald, introduced in series 7, died three times before she became a regular companion, though on the last occasion she got better.
The series finale takes the cake though and possibly sets a record: Thanks to inserting herself into the Doctor's timestream to undo the damage caused by the Great Intelligence, Clara has lived and died thousands of times in order to save the Doctor.
The original MacGruber shorts all end with the team failing to disarm the bomb and the building they're in blowing up. Despite this, the shorts in each episode refer back to one another, and dialogue suggests that they see the bombs as threats to the buildings rather than themselves. Don't ask how.
Daniel Jackson of Stargate SG-1 dies a lot. The Other Wiki used to have a list, in fact. Depending on whether or not you count androids, alternate realities, and virtual reality simulations, he's over 20. Even disallowing every single time he didn't actually die, he still died at least four times. That might not sound like a lot for this page until you consider that in-universe, he's just a Badass Bookworm with no actual special abilities. It's not that he's a Sufficiently Advanced Alien, he just keeps on being saved at the last minute or seeing duplicates of himself get killed. After the second time he died (ironically, one of the times he wasn't really dead), his friends basically gave up on even giving him a funeral. Eventually it did become a Running Gag that some of the other characters (Jack) just stopped buying it whenever someone claimed that "They killed Danny!".
Charles Kawalsky dies a fair bit too, but is never actually resurected. Originally died in the 3rd episode, then an alternate reality in episode 20, then from another reality in season 6-06, and finally in an alternate timeline in 8-20. Really, any time he meets people from earth prime, it's gonna be a bad day. I think he died in the book continuation of the movie too, but that's non-canon and not tied to the series timeline.
A Season Five episode of Supernatural actually opens with a montage of scenes from previous episodes where Sam and Dean "died," along with Bobby Singer snarking "how many times have you two died?"
Mongrels has one episode where Marion dies eight times if you count all the Family Guyesque-flashbacks, but otherwise averted unlike a lot of the "adult" cartoons it draws inspiration from.
Similarly, expect any recurring immortal in Highlander to die and come back to life several times. Unless the death involves decapitation, it's only an inconvenience to them.
One of the few times it's played for drama is Pygmon from the Ultraman series. Everytime the little guy shows up he normally gets killed, or at the very least, severely injured or threatened. While in universe this is played for the drama, and can be a Tear Jerker, he's earned the reputation in the fandom as the Kenny of Kaiju due to this.
Kennedy Smith and Allan Kriegman, the feuding retired secret agents and lead characters of The War Next Door, are prime examples of this trope. At least one of them dies at the end of every episode.
The Young Ones ended several episodes by killing off all four of the lads, and Neil died once in addition to that. Subverted with Vyvyan, who suffered injuries a few times that would've been fatal for anyone else, but shrugged them off.
Neil didn't die when Rik clouted him with that shovel. "Good thing Rik only stunned me, eh?..."
Jack Harkness of Torchwood and Doctor Who gets killed numerous times, but he's immortal, so it doesn't stick.
Due to the fact that he's literally a crash dummy, Buster from MythBusters is "killed" frequently by being put in situations that most often would be fatal to any actual people who were subjected to them. There have also been a few occasions where Buster has been so trashed that he's had to be completely rebuilt.
Vocaloid's Len Kagamine and Kaito both have a reputation for getting killed off in many of their songs and music videos.
"But the cat came back, the very next day. They thought he was a goner but the cat came back 'cause he wouldn't stay away!"
Bill the Cat in Bloom County was a frequent example of this in his earlier days in the strip. Notably when he's electrocuted by his tongue being wired into an amplifier while rehearsing with Deathtongue...
Steve Dallas: ...AW, FERCRISSAKES, he isn't dead AGAIN, is he?
Portnoy: ...Naw, naw...I'll get the Bactine.
Brewster Rockit play this one for laughs with pretty much everyone, especially Winky, Dr. Mel's unfortunate assistant, who seems to be able to lose his spleen many, many times. The comic at least used to have an Ensign Kenny, but Winky basically fills in for him.
Show Within a Show version: In Pearls Before Swine, Rat's "Angry Bob" stories tend to have the titular character die in all sorts of absurd and gruesomely comic ways, only to be alive at the start of the next story with no explanation (though in a few occasions Rat did write that Bob "undied")
The Brudderhood of Zeeba Zeeba Eata crocodiles either suffer from this or are defying the One Steve Limit.
Generic Ted in Dilbert is fired frequently, and has actually died more than once. The cartoon suggested that the company has several identical looking guys named Ted.
The later British radio comedy series The Burkiss Way featured the character of Eric Pode of Croydon, most of whose appearances ended with him getting shot by whoever he was talking to, usually the long-suffering Fred Harris. On one single occasion, Pode shot Harris, announcing 'I had to do that, he was getting on me nerves.'
The early "Guy Noir" sketches on A Prairie Home Companion (and its 80s substitute, Garrison Keillor's American Radio Company) were set up in this manner, with the title character and his then-sidekick, Jimmy, repeatedly accidentally killing each other. After the Moral Guardians protested these violent acts, Jimmy was Killed Off for Real and "Guy Noir" adapted its current format, with Noir getting by on his wits alone.
It's not uncommon for adaptations of Dungeons & Dragons to parody the relative ease in which dead PCs can be resurrected.
Any video game where the player's character can be killed can be this if the player is bad or the game is hard. Some games try to find creative ways of making every death part of the actual plot.
One interesting example of this is the Vita-Chambers in BioShock. In the technologically advanced underwater city of Rapture, there are chambers scattered throughout that can actually resurrect the main character if he's killed. The reason this doesn't work for the enemies in the game is because the main character turns out to be Andrew Ryan's son, and the Vita-Chambers were attuned to Ryan's genetic code when the civil war in Rapture broke out. So the chambers only work for Ryan and his blood relations.
The Carmine Brothers from Gears of War. Clay is an exception.
Gamon from World of Warcraft is a player based version of this. He's the only NPC in all of Orgrimmar that can be attacked, and due to his low level and the fact that he's sitting in an inn (where people usually hearth to after questing), he seems to exist solely to die over and over again. This is somewhat infuriating to low level rogues who need to pickpocket him to complete a class-based quest. He later appeared as a card in the World of Warcraft trading card game with the flavor text "Not again!"
Maria in Silent Hill 2 dies multiple times throughout the game with no knowledge of dying, however James fully remembers the deaths and is completely confused about the situation.
There is a running gag in Live A Live where each chapter whenever somebody says Watanabe, a random person will get killed, and usually a son will run in streaming tears dragging them away. Not played for laughs in Cube's chapter.
And BLU Heavy, who was killed in Meet the Soldier (off-screen), Meet the Demoman (gets caught in a sticky bomb explosion), Meet the Engineer (shot off-screen), Meet the Sniper (shot in the head), Meet the Spy (stabbed off-screen), and Meet the Pyro (axe to the head).
The Ship Captain in God Of War gets killed by Kratos on three separate occasions. In the first game, Kratos deliberately lets him fall into the belly of the Hydra, then when they meet in the Underworld, Kratos kicks him into the Styx and leaves him to drown as he escapes. When the Barbarian King summons the Captain as an undead minion to do battle with Kratos in II, he screams "No! Not you again!" before Kratos kills him.
Lynne from Ghost Trick. The game has 18 chapters, 5 of which feature her dying and you being forced to go back and save her. She can, of course, die many more times if you fail at said "saving" often enough. Eventually, she herself stops taking her deaths seriously. Also, she almost dies once more in the last chapter, just before Sissel decides that he's had it with Lynne dying and stops it before it happens.
Sissel: It's Lynne! And she's not dead, for once!
Demon's Souls as a whole makes the player character this Trope; a lower then average player can expect to die at least 100 times. Quite possibly all on the 1st level.
Time Crisis: Wild Dog, the villainous mascot of the series, is always blown up in every game, only to come back in the next game for more. His apprentice, Wild Fang, also gets in on this habit, from being fatally shot to getting his spine crushed by a speeding plane.
At least one member of the Teen Girl Squad dies comically at the end of almost every issuenote The exception being 2, only to return without explanation between issues.
Happy Tree Friends: Most of the cast, with Cuddles (just barely) in the lead. Mole is the only character not to have died in the series itself, although he did in a cutscene from the video game adaptation.
The reason Mole has not died as frequently as the other characters in the main series is kind of touching: he's blind. So is the daughter of one of the creators.
Mole has died several times in the latest season of Happy Tree Friends - most notably, during the episodes Concrete Solution and Idol Curiosity, as well as fifteen other deaths from regular episodes alone. Normally, however, Mole is one of the characters responsible for the deaths of others.
In Dinosaur Office, any time the Intern appears, Terry (a tyrannosaurus and their boss) eats him not long afterwards.
Homestuck takes this trope in a slightly more serious and infrequent direction - John has died three times already, twice not counting Bad Futures, and all in the same day owing to an extreme case of Webcomic Time. The first time led to him becoming a Physical God, so now he's pretty much immortal - as Karkat keeps pointing out, he also keeps proposing ideas which will likely result in him dying again. Hussie lampshaded this in a news post about an imminent move of his:
Moving seems to have become an annual tradition, just like killing John has.
Yaythunder from Bad Drama dies at least once in all six story arcs of the 150-strip comic (twice in the second story arc, though his first death in that arc occurred in a dream world). Yaythunder's deaths appear to be a direct reference to Kenny's deaths on South Park, especially considering the utterance of "Oh my god, they killed Yaythunder!" and "You bastards!" in response to his first death. David, Yaythunder's equivalent in the Bad Drama remake Landslide, has not died so far and it is not clear yet if that running gag will still be used.
Ctrl+Alt+Del's early strips would feature Ethan getting killed every once in a while by ninjas or arrows fired from off-screen. The other characters don't pay much attention, as if this were absolutely normal, and Ethan (being the main character) is invariably alive and well in the next strip. Players 1, 2, 3 and 4 also get regularly murdered in gruesome fashion, only to come back to receive the same treatment.
This running gag stopped for awhile after doing a Doctor Who parody for an April Fools joke, where he became someone else and then became himself again. He almost never dies by the end of the episode unless he lampshades it.
He does this again for To Boldly Flee, with actual "in-story" reason: he is a Red Shirt. Whenever a redshirt is killed, there is always one more just like it (although usually with a different name) waiting in the ship. He is their only redshirt. Thus, whenever he is killed, there is suddenly another Phelous waiting in the ship. Or, to put it another way, he's running simultaneously on Original Series rules (the Red Shirt trope) and Next Generation rules (in which red shirts are important characters).
Death Is Cheap in Ink City, and Ren tends to die a lot. The fact few of the other residents seem to notice or care make him even bitterer than usual.
As a reference to her counterpart Aerith's death, the character Aeromite from the Kingdom Hearts parody Kingdom Paf gets killed several times in gruesome ways, only to ALWAYS come back alive a few minutes later.
A justified example in Flander's Company: villain-wannabe Kevin is explicitly stated to have the ability to resurrect each time he is killed; sadly for him, he also has the ability to piss off Hippolyte, who takes advantage on this power to kill him as many times as he can in always more gruesome ways.
The Madgie, what did you do? series Madgie is this or, occasionally, some of the stories has it where her fate is ambiguous but in most of them has it that she dies, often in horrible ways, ever since the second story to the rest. She gets better once time is reversed back to the way it was.
Actually, ANYONE that dies in series is like this, however, Madgie dies the most. This should be noted that this isn't for comedy, rather, in the first instance, it was to make the story moe poignant.
Icarus in Dragon Ball Abridged. After Goku mentioned him during his fight against Vegeta as a pet of Gohan's who died before the series even began, he has since reappeared alive and well in the Abridged Movies... where he has gained a tendency to get cooked and eaten by Gohan's family by the end of each movie.
Justified in the SCP Foundation with Dr. Bright uses SCP-963, which transfers his consciousness to the next living thing to touch it. That said, the original Bright is long dead, and so are lots of replacement bodies.
Todd in the Shadows tried to make a running gag out of being Driven to Suicide, but dropped it after the second instance. Not before having a chance to lampshade it, though: "Once again, my faith in pop music has been destroyed, which means that once again, it's time to kill myself."
In South Park: Bigger, Longer & Uncut, Kenny dies for real however, and goes to hell. He is resurrected only when the forces of Hell invade Earth, and sacrifices himself so that there will be no Hell on Earth. Luckily, he then finds out that he's going to Heaven this time.
This is lampshaded in a few episodes, particularly in "Cartmanland"
"...and the rest of the money is owed to the family of a boy who died on one of your rides."
"Kenny?! He dies all the time!"
In later seasons they've taken to subverting/averting this trope. For example, in "Poor and Stupid," Kenny finds himself on an active NASCAR track while accidents are happening all around him and cars are ramming each other trying to win, and manages to not get killed. In other episodes, they use him to avert Like You Would Really Do It. The audience is so used to seeing him die, that whenever they want to have real tension in a potentially fatal situation, they stick Kenny in there.
And now, it seems that Mysterion is Kenny, and he has been completely aware of these multiple deaths all along, though no one else is much to his annoyance. The three-part episode deconstructs and explains the mechanics of his "power." There are still some plot holes (for example, his resurrection in "Cartman's Mom Is Still A Dirty Slut"), but for a show with Negative Continuity and Multiple-Choice Past it's oddly cogent.
Actually it could be explained that his reappearance is really their memories of his death being wiped away. They act as if he walked back to them.
It is - he shoots himself in the head during the Mysterion trilogy after stating he's tired. He awakens in his bed and all the South Park kids as their hero identities show up at his door asking him why he just ran away like that. The same thing happens when he gets knifed in a fight with the others.
Non-Kenny example: In "Probably," Satan's caught in a Love Triangle, with his two potential boyfriends (Saddam Hussein and some random dude) constantly killing each other. However, since they're already dead and in Hell, this just means they disappear for about a day and show up again with the next batch of damned souls. ("Where was I supposed to go, Detroit?'')
Osama bin Laden has been killed twice on the show (maybe three times if the events of his real life death occurred in their universe).
Cartman seems to have this gift, to a lesser extent. In the 1992 pilot (Jesus vs. Frosty), he's killed off, but then in the next episode revived with no explanation. Oh, and in Medicinal Fried Chicken his head exploded. Next time we see him, he's fine.
Virtually every cartoon featuring Wile E. Coyote has the coyote suffer amusing injury after amusing injury with seemingly no long-term consequence. But occasionally, the final backfiring trap has apparently killed him:
In "To Beep or Not to Beep," where he makes six attempts to use a catapult to hurl a large boulder on top of the unsuspecting Road Runner. Each attempt fails, often in comically spectacular fashion; the sixth attempt has — after much prodding — the catapult finally working (he jumps up and down repeatedly to get it to unjam ... only for him to be hurled toward a large rock formation and then a series of electrical transmission lines, after which he is hurled back to the catapult and finally killed. (After Wile E. is finally flattened, the catapult's manufacturer is revealed — The Road Runner Manufacturing Co., the Road Runner on the name plate "beep-beeping" for joy as he runs off.
In his pairings with Bugs Bunny, the most spectacular deaths come in:
"Operation: Rabbit." In the final gag, Bugs uses a tractor to pull away a shed (where the Coyote is busy pouring nitroglycerin into carrots) and unhooks it on some railroad tracks ... just in time for a train to be coming. The train hits the shack, resulting in a huge explosion and sending Coyote high into the air. The dazed Wile E. lives long enough to visit Bugs one last time and admit defeat.
"Compressed Hare," where in the final gag, Wile E. builds a 10 billion-volt magnet to — after getting Bugs to eat a metal carrot — pull his prey to his cave for an easy dinner. However, not only does Bugs send the carrot back, but the magnet begins pulling everything with metallic properties toward Wile E.'s cave, trapping him inside as the final object, a Mercury rocket attempting liftoff, is pulled into the cave; immediately thereafter, everything explodes and (presumably) kills the Coyote once and for all.
On one occasion, he blasted himself into space on an out-of-control rocket sled which explodes and turns him into a constellation of stars.
N.I.G.E.L in Godzilla The Series was destroyed or heavily damaged in just about every episode. Of course, being a robot, the crew would often send him into dangerous situations so they wouldn't put themselves at risk.
Buzz Lightyear Of Star Command has XR, who was built by the LGMs for the purpose of being practically indestructible- he could be reassembled from ludicrous amounts of damage. In the prequel movie, he gains his 'human' personality and improbable equipment loadout from being incorrectly repaired while the LGMs were in disarray. Thus, in pretty much every episode he is destroyed, disassembled, taken over, torn apart, and otherwise suffers all kinds of Amusing Injuries and complains about it all the while.
Sealab 2021 has the whole base blow up with all hands in several episodes. It once led to the line, "Once again, your stupidity has killed us all!"
Note that this was the very first episode of the show, period.
Dr. Quinn: "You know Sealab is prone to massive explosion!"
The Simpsons: Hans Moleman dies in just about every episode he appears in.
Apparently the folks at Mainframe believe in kharma: after being the ignominious Butt Monkey for the entire show, at the end of the big finale the Predacons are either destroyed or imprisoned, the Maximals are on their way home... And Waspinator is still on Earth, living large as the king of the proto-humans.
Something happens to Eustace from Courage the Cowardly Dog in every episode. In the pilot, he was shot by a ray gun and reduced to a cinder, but other episodes just have him suffering some horrible fate that there doesn't seem to be any way to reverse.
Futurama had a minor character, a used car salesman named Malfunctioning Eddie. Every episode he appeared in, his head exploded at some point. Of course, being a robot, he was always fixed by his next appearance.
The various members of the Waterfall family are always killed off at the end of the episode they're featured in, with the Waterfall that will be featured next time lamenting their demise.
The entire cast has died at some point at least once, most notably the first Comedy Central episode (Rebirth) when everyone BUT the Professor died, and the Professor himself often declares himself to not be technically alive. In the episode Ghost in the Machines, even the robots Bender and the Robot Devil die during the episode and are alive again before the end of it, which is amusing considering in the prior season Bender was told he'd killed off for real if he ever died. The episode doesn't technically violate continuity, since Bender wound up in his same body while the Robot Devil downloaded to a new one.
Even the city of New New York and Earth itself have been Kenny'd several times, from being scorched from the Omicronians to being consumed by a Grey Goo of Benders, only to be rebuilt perfectly in time for the next episode. Even lampshaded during one such ending.
Virtually everyone in Squidbillies. Most common targets being Rusty, the Sheriff, Granny, the convenience store guy, and Early himself. Technically justified for the Sheriff, as it's revealed he's actually one of hundreds of identical Sheriffs grown in a field, all just as stupid and incompetent as him.
In most episodes of The Venture Brothers H.E.L.P.eR. has something horrible happen to him, including being sent into orbit around the Earth and shrunk to ant-size and stepped on. Of course he's a robot so it's likely that he gets repeatedly fixed up. As well, Hank and Dean are shown in the first episode of the second season through flashback to have been killed/died and then re-animated via cloning many, many times.
Sylvester J. Pussycat from Looney Tunes died the most out of any golden age cartoon character at 16 deaths in 8 cartoons with one of them losing all nine of his lives one at a time, but he always came back when he was needed.
Fluffy and Uranus the teddy bear secretaries from Duckman died in every episode they appeared in except one.
The entire cast of Drawn Together is subject to this, with Toot and Ling-Ling dying the most.
Somewhat justified with Xandir, as he is a video game character with numerous extra lives in reserve. In one episode, however, Ling-Ling was so angry with him that he killed off all of Xandir's extra lives, though that didn't stop Xandir from coming back to life the next episode anyway.
Totally Justified. He used a CONTINUE after that one.
Lampshaded by Wooldoor in "Lost in Parking Space, Part 2": "We can't just keep dying and coming back to life the next episode! IT'S TOTALLY ILLOGICAL!"
After which Ling-Ling appears to say he agrees with that—two minutes after dying himself.
Finally subverted in the movie as, since their show was canceled, there was no Negative Continuity to glean from to resurrect them. Once they were dead, it was for keeps.
Robot Chicken has the host of the Blooper shows, who always ends the show by killing himself. The entire show's staff has been killed at least once as well.
Tom of Tom And Jerry has died at least three or four times, not counting the short Heavenly Puss which was All Just a Dream. He's been executed in Revolutionary France in The Two Musketeers, and in another cartoon is blown up and floats upward toward Heaven after a failed attempt to catch Jerry. But of course he's back next cartoon as if nothing happened.
Daffy Duck has died four or five times: first in "Daffy and the Dinosaur" when a giant inflatable duck he set up and goaded another character into attacking exploded and both are last seen as angels on clouds with Daffy remarking that maybe the whole gag "wasn't such a hot idea after all". In "Draftee Daffy" when the rocket he's riding on crashes and explodes and his soul is last seen in Hell. In Duck Dodgers in the 24½th Century he is vaporized by Marvin the Martian (but revived by Porky so this one may not count), in "The Scarlet Pumpernickel" he may or may not have died after shooting himself in the head, and in "Show Biz Bugs" he swallows a bunch of explosives and tosses a lit match down his throat causing himself to explode and is then seen as a ghost.
The title characters of The Ren & Stimpy Show died at the end of many of their shorts, most notably in "Terminal Stimpy" when Stimpy keeps getting killed and he tries to stop himself from losing his last life.
Muddy Mudskipper has died at least three times, in "Powered Toastman" he is left behind on an exploding dynamite keg and his skeleton is seen flying from the debris of the explosion, in "Bass Masters" he is seen as a trophy mounted on a wall, and in "Terminal Stimpy" he is run over by Stimpy and after his dying wishes are fulfilled he asks Stimpy to be skipped across a pond and he is then hit by a bus and his corpse is seen sticking to the grill.
Scarface the Ventriloquist's puppet from Batman The Animated Series is destroyed at the end of every episode he appears in. The creators said they went out of their way to give Scarface the most gruesome "deaths" they could, which they'd never get away with if he was a human, because hey, he's a puppet, so it's okay.
A running gag in Celebrity Deathmatch was Don King getting killed randomly during matches; he eventually had a deathmatch himself against Donald Trump who kills him for the last time in the series when he climbs down his throat and tears him apart from the inside.
In Jackie Chan Adventures when Dao Lon Wong turns Finn, Chow, and Ratso into Dark Chi Warriors they got killed multiple times per episode exploding into dust every time they do so, until they are changed back. Uncle explains that Wong had the power to resurrect them any time he wanted.
In the Private Snafu shorts, the title character died in 6 out of his 15 shorts all due to his stupidity; these were made to teach soldiers what they shouldn't do when in the army.
In Superjail the fat, balding, lecherous inmate (the one who wants to show you his penis) gets killed several times but is always shown as a recurring character.
Actually this extends to all of the inmates of the prison in general.
The leader of the lunch ladies is often killed or maimed in some sort of fashion. If there are a group of them around, chances are the rest will suffer in some way too.
Justified with SpongeBob; it's explicitly shown he can regenerate.
Also in SpongeBob, a fish named Scooter apparently drowned when SpongeBob left him buried up to his neck on the beach. He appeared later in that episode as a ghost/angel. Let that sink in for a few seconds.
Scooter was seen alive and well in later episodes but died on two other occasions. In "Something Smells" SpongeBob's stinky breath killed him and another fish and in "My Pretty Seahorse" after he thinks Mystery the seahorse is a ride and inserts a coin into her she kicks him and he explodes where he lands.
In Woody Woodpecker his nemesis Buzz Buzzard died in a couple of shorts. In "Wild and Woody" Woody locked him in a stove and threw dynamite inside causing it to explode and then guides his soul to hell, in "Buccaneer Woody" he lights a match in a gun barrel he's carrying and after it explodes he's seen as a ghost, in "Scalp Treatment" he's blasted off into the distance with a large explosion where he lands, and in "The Great Who Dood It" he launches him into space with exploding cigars.
Woody himself has died in a couple of cartoons such as "Ration Bored."
There's a series of short films based on a picture book named "The Many Deaths of Norman Spitall," in which the title character would die or be executed by quirky methods.
Peter's died a few times, but he's tight with Death. Except when he WAS Death.
Bluto from Popeye has died in a couple of shorts like in "Blow Me Down" after being punched around the world twice by Popeye he falls to the ground with x's on his eyes and in "We Aim To Please" at the end Popeye punches him into a wall where he lands on a meat hook and he turns into cuts of meat labeled "a bunch of baloney"
In the South Park parody segment in the Arthur special episode "The Contest", Buster's character fell victim to this trope after aliens landed directly on top of him right when he told the aliens to land. Staying true to the source material, Francine's character shouts "Hey! You squished Buster!"
Many of Chris's interns in the Total Drama series end up dying in various horrible ways only to come back perfectly fine in future episodes.
Donald Duck may have died at least three times. In "Uncle Donald's Ants" after getting sick of the ants invading his house he attempts to blow them up, resulting in him blowing himself and his shed sky high instead. The cartoon ends without seeing him come back down. In "Dragon Around" Chip and Dale attach explosives to his ladder, again blowing him into the air, and like the previous entry he isn't seen again. In "All In a Nut Shell" Donald is knocked unconscious and Chip and Dale place him in a log then stuff a bee hive into it. When the bees sting Donald he goes bolting out of the log like a cannonball into the horizon. Chip and Dale hold their hats while "Taps" plays and they laugh.
Another Looney Tunes character to get this treatment is Yosemite Sam. In the short "Devil's Feud Cake", Sam has a run-in with Bugs Bunny and gets himself killed. He finds himself in Hell, where the Devil offers to bring him back to life if he can send him Bugs's soul to take his place in Hell (by killing Bugs). Sam ends up getting himself killed a second time while going after Bugs, so the Devil "gives him another chance" and sends him after Bugs again. After dying the third time, Yosemite Sam tells the Devil that if he wants Bugs so badly he should go get him himself - he's staying put this time.
He also died at the end of "Dumb Patrol" after his plane crashed into an ammunition dump and he's last seen as a spirit in a devil costume strumming a harp.
Elmer Fudd died at least twice. After being buried alive in "The Old Grey Hare", Bugs hands him a huge stick of dynamite and the explosion rocks the title card as the ending plays. In "Back Alley Oproar" he is fed up with Sylvester's singing so he plants a bunch of dynamite around the fence; it explodes as he lights it, killing both of them. He's seen as an angel on a cloud surrounded by Sylvester's past 9 lives (still singing). This last one may or may not count but in the ending of "Hare Do" he is eaten by a lion but he's still alive before the Iris Out.
It's also possible he died at the end of "Ant Pasted", Elmer is at war with a colony of ants who use firecrackers as arsenal, at the end Elmer gathers up the remaining firecrackers and runs away yelling "You'll never take me alive!" unknowingly leaving a trail of gunpowder behind, the ants light the powder and blow him up in a massive explosion and you don't see him after that.
Zorak from The Brak Show died at the end of a lot of episodes, most commonly being shot or blown up.
Rigby from Regular Show has died or almost died on multiple occasions, often getting better through supernatural means.
Harry Sachz the man whom Beavis And Butthead prank phone called repeatedly to make fun of his name died twice, the first time was in "Butt Flambe" when he received a gunshot wound and later died in the hospital and in "Nothing Happening" he is killed during a standoff with the police, he came back both times with no explanation.
Archer has a not-quite-fatal example in a random office employee who is always hit off-camera by Archer's stray bullets. The running gag is that Archer will accidentally fire his weapon in the office, prompting an "Ahhgggh! God... dammit Archer!" from offscreen. The man is never quite finished off, and we occasionally see the him covered in bandages and/or lying in a pool of his own blood.
At the New York Renaissance Faire, Sheriff of Nottingham Philip De Marque has been killed off a number of times at the end of many years' story lines.