Given that Sherry is quite the Woobie who tends to hug Claire a lot she can get a few 'Awww's' out of the player.
Doubly so during gameplay if you have Sherry following you and you stand still. When she catches up to you, if you don't move, she holds Claire's hand until you move again. A very sweet example of passive Video Game Caring Potential.
Leon and Ada having a tender moment in 2 after Birkin injures Ada and Leon fights him off, seen here.
Leon: I told you, it's my job to look after you.
Ada: But, you'll be in danger if you stay with me. I know I've only known you for a short period of time, but I really enjoy being with you.
Ada: I know, I'm not capable of caring about anyone, but, I don't want to lose you.
All the times Ada helps and saves Leon from then on shows she means it.