At the end of the B scenario, when the Tyrant reappears outside the train, both characters have their own one-liners as they deliver the finishing blow:
Leon: "Game over."
Claire: "You lose, big guy!"
The fact that Leon—21 years old, pre-government training, and what was to be his first day of work—continues kicking ass and killing monsters through the entire second half of the game with a bullet in his freaking shoulder.
The last line delivered in Leon B:
Leon: Hey, it's up to us to take out Umbrella. (roll credits)