We get a lot of these in the South Haven arc, most of them involving Aron and Trixie, who apparently can't hold her scotch well.
Like when Trixie explains how she's not at all uncomfortable living in South Haven (a clothing-optional community), having been born and raised there. The little Sight Gag with her parents makes it funny:
Trixie: There's my parents. (Waves) Hi guys!
(Cut to panel of Trixie's (just as naked) Mom and Dad.)
Followed by Beth introducing Trixie to scotch, stating its "kind of like wine," which turns out to be Trixie's drink of choice, convincing her to try a glass or two. As Beth explains that you have to "savor the complexities of the flavor," however...
The segues back to Lynne's story have a number of these as well, with moments of Self-Deprecation and Creator Career Self Deprecation most likely playing a part in her struggles and annoyances as a webcomic artist and freelance artist.
The reveal that Brice (Sissy's husband) isn't seeing anyone, and only asked for an open marriage because he knew that it would drive her nuts, and that by making himself "available" to others, he'd be more attractive to her, flying in the face of her psychosis. The revelation that "men can be just as devious as women" is apparently too much for Elizabeth to take, as she just sits there dumbstruck while Fisk nonchalantly takes a sip of his coffee.