We get a lot of these in the South Haven arc, most of them involving Aron and Trixie, who apparently can't hold her scotch well.
Like when Trixie explains how she's not at all uncomfortable living in South Haven (a clothing-optional community), having been born and raised there. The little Sight Gag with her parents makes it funny:
Trixie: There's my parents. (Waves) Hi guys!
(Cut to panel of Trixie's (just as naked) Mom and Dad.)
Followed by Beth introducing Trixie to scotch, stating its "kind of like wine," which turns out to be Trixie's drink of choice, convincing her to try a glass or two. As Beth explains that you have to "savor the complexities of the flavor," however...