It gets this a bit with She-Ra and the Princesses of Power, as both shows have a female protagonist in a magical land with a jealous, toxic ex-best friend serving as the right hand to a major villain who is trying to conquer said land. Even the season 2 opening, which includes a fight sequence between Anne and Sasha, brings to mind the fight sequence between Adora and Catra in She-Ra's opening theme.
To a lesser extent, there's a good number of viewers who see Anne and Sasha's relationship as somewhat similar to Catra and Adora's, with a few people actually starting to ship them. The similarities became greater in season 2, wherein Anne, much like Adora, becomes something of a Love Martyr who is determined to get her best friend back despite the fact that Sasha, like Catra, is clearly causing massive harm. Sasha doesn't take the end of their friendship well, to the point that she doubles down on villainy, and ends up making the exact same mistakes as Catra did in her quest for power where it comes at the expense of others, driving away those who care about her as they decide she's not worth sticking around for. Both Sasha and Catra make one final betrayal that severely damages their relationship with Anne and Adora, as the latter decides they have had it with their selfish and hurtful behaviors and are Beyond Redemption, and don't even want to hear anything they have to say anymore. To top it all off, Sasha ends up Lonely at the Top and arrives at the same realization as Catra, initially believing winning would be satisfying, but finding once she has it that it's not, and questions if power was worth burning all her bridges to get.
Of course, Marcy has netted comparisons with Entrapta, as both are quirky science-minded young women who show signs of having ADHD and/or autism.
Interestingly, both shows also have multiple LGBT shippings and a growing LGBT Fanbase. Both protagonists are also commonly shipped with their female friends. The only difference is that while Luz is confirmed to be bisexual, with Amity being her canon love interest, Anne is Ambiguously Gay and her bonds with Marcy and Sasha remain as platonic with a ton of more romantic subtext.
This has grown after both shows ended with the finales of both shows featuring the female main protagonist sacrificing her life for others, and dying in front of her Found Family, meeting a deity-like entity, and coming back to life, and getting a Super Mode, becoming a Physical God in the process who battles her series' respective Satanic Archetype alongside two of her closest allies and friends, though in differing orders of events, and ultimately end with the protagonist becoming a Messianic Archetype and end with their own Distant Finale.
Matt Braly also appears to be a fan of the show, with him following the Powerpuff Girls creator Craig McCracken on both Twitter and Instagram. In addition, Amanda Leighton, the voice of Polly Plantar, voices Blossom in the 2016 reboot of The Powerpuff Girls.
Many fans believe that the colors of the Calamity Box bear a strong resemblance to the main colors of the three members of The Powerpuff Girls: pink for Blossom/Sasha, blue for Bubbles/Anne, and green for Buttercup/Marcy. Fans have also pointed out strong references to The Powerpuff Girls, such as the girls flying off with their Calamity powers from the promo for the finale, "The Hardest Thing", as a reference to how Blossom, Bubbles, and Buttercup fly, and the red and black screen showing Marcy getting possessed from "Olivia and Yunan" bearing a strong resemblance to the part of the intro from The Powerpuff Girls with the Professor accidentally dropping Chemical X.
And, both second seasons of this show and Tangled: The Series have the same premise of the main female protagonist venturing through parts unknown on a caravan with their friends to a faraway land to seek answers to the mysteries of their current situation.
The fandom of Hilda is also giving the show love as well, because Anne has a fearless spirit and is always looking for adventure, just like how Hilda does. What both shows have in common is that they are sleeper hits and are easily overshadowed by popular shows such as She-Ra and the Princesses of Power, for Hilda, and The Owl House, for Amphibia. In addition, both protagonists have a thing for befriending magical creatures.
It is also Hilarious in Hindsight because both the second seasons of Amphibia and Hilda ended on a massive cliffhanger, and both shows came to an end after three seasons.
Oddly enough, with Onyx Equinox, since both creators are friends in real life (Matt Braly even being one of the very few content creators in the animation industry to give a shout out to the series). Conversely, Sofia Alexander defended the staff during the controversy surrounding members of the crew making Sasha x Grime content.
While not a cartoon, Olivia Rodrigo's SOUR album is very popular among Amphibia fans, with many animatics, AMVs, and a few fics being made with her songs. The album is usually associated with Anne, Sasha, and Marcy, and is used to detail the trio's deteriorating relationship with each other, adding romance to the mix as well. The most popular songs to use in such fanworks are "brutal", "traitor", "good 4 u", and to a lesser extent "deja vu" and "favorite crime".
There is a bit of this with Dragalia Lost, despite the latter being quite obscure. The show and the game have had similar lifespans (Mid 2019 to Mid 2022 for Amphibia and Late 2018 to Mid 2022 for Dragalia Lost [although it officially shut down servers in late 2022]) and have been made by companies that are often compared toeach other. They are often overshadowed by a different show or game (The Owl House and Fire Emblem Heroes). They have similar premises of having a main character (Anne and Euden respectively) who gets separated from the people that they were closest to, and with no way to return home, they end up moving to a small area, where they meet a small group of friends that they always travel with. They then spend most of their time early on simply helping all the people around town, but there is eventually some serious Cerebus Syndrome. Both series even end with Anne and Euden unlocking a Super Form, at the end, their bodies get destroyed, but they end up getting copied. There is also a robot character (Frobo and Laxi/Mascula) that the characters meet in the middle of their journey who seems antagonistic at first, but is actually a Rogue Drone who is a pacifist, and they develop a friendship with one of the main characters in particular (Polly and Luca).
Anne and Euden aren’t the only ones who share similarities either; Sasha has been compared to Leonidas, and Marcy has been compared to Zethia. For the former pair, they have similar designs, with their red-ish armors and long, blond hair. They’re both tyrants related to the protagonist, who have a loyal companion(s) who eventually leave them, have a climactic battle with the protagonist, and eventually have a Heel–Face Turn where they end up leading the people who were usually ruled by the protagonist while the protagonist was away. As for Marcy and Zethia, they are both the one who started every event that in the series, as they did something foolish since they thought it was best for the ones they were closest to. They develop a connection to the main villain, and eventually, they end up getting possessed by them, which the villain uses to become a tyrant. Once their freed, both Marcy and Zethia also end up getting a Super Form alongside Anne and Euden, which they use to help defeat the Big Bad.
Shortly after the show ended, Xenoblade Chronicles 3 was released, and same fans immediately saw it as a successor of sorts. Both stories involve a group of three friends exploring a different world (Anne, Sasha, and Marcy, and Noah, Eunie, and Lanz respectively), while they find friends from said world whom they always travel with. The main character (Anne and Noah) gets especially attached to one particular person from said world (Sprig and Mio), and their blossoming friendship is one of the main aspects of their respective series. The two main villains are also incredibly similar with King Andrias and N having incredibly similar backstories, and The Core and Z having similar overall concepts behind them.
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